Evidence map›Paper›PMID 34573094›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Plant Feed Additives as Natural Alternatives to the Use of Synthetic Antioxidant Vitamins on Livestock Mammals' Performances, Health, and Oxidative Status: A Review of the Literature in the Last 20 Years.

Carmen L Manuelian, Rosario Pitino, Marica Simoni, Alexandros Mavrommatis, Massimo De Marchi, Federico Righi, Eleni Tsiplakou

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  15. Verbascoside-Rich Plant Extracts in Animal Nutrition.Antioxidants (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carmen L ManuelianDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell' Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-0090-0362
Rosario PitinoDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.ORCID 0000-0002-6784-8167
Marica SimoniDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.ORCID 0000-0003-3920-9744
Alexandros MavrommatisLaboratory of Nutritional Physiology and Feeding, Department of Animal Science, School of Animal Biosciences, Agricultural University of Athens, Iera Odos 75, GR-11855 Athens, Greece.ORCID 0000-0002-0497-2750
Massimo De MarchiDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell' Università 16, 35020 Legnaro, Italy.
Federico RighiDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.
Eleni TsiplakouLaboratory of Nutritional Physiology and Feeding, Department of Animal Science, School of Animal Biosciences, Agricultural University of Athens, Iera Odos 75, GR-11855 Athens, Greece.ORCID 0000-0002-2544-8966

Funding

European Union's Horizon 2020 research and innovation programme 774340
6 · The paper itself

Abstract

In the last two decades, the interest in natural plant feed additives (PFA) as alternatives to synthetic vitamins in livestock nutrition has increased. After a systematic review, a total of 19 peer-reviewed papers published between 2000 and 2020 were retained to evaluate the antioxidant effects of PFA compared to synthetic antioxidant vitamins (mainly vitamin E; VitE) in livestock nutrition. These studies demonstrated that PFAs could be as efficient as VitE in counteracting oxidative stress in pigs, rabbits, and ruminants. However, PFAs only positively affected animals' growth performance and feed efficiency in some monogastric studies. The PFA can affect antioxidant enzyme activity in a dose- and method of administration-dependent manner. The antioxidant capacity of both PFA and VitE were depressed in cows fed with diets rich in polyunsaturated fatty acids. Variability among studies could be related to species differences. Despite the interest of the feed industry sector in PFA, there are still very few studies evaluating their antioxidant effect in species other than poultry.

Indexed as

antioxidantsessential oilsnatural vitaminsplant by-productplant extractsynthetic vitaminstocopherolstocopherylvitamin Cvitamin E

Identifiers

PMID34573094
PMCPMC8464857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.