Evidence map›Paper›PMID 34573057›Full record

ArticleAntioxidants (Basel, Switzerland)2021

The Impact of Cardiovascular Rehabilitation on Psychophysiological Stress, Personality and Tryptophan Metabolism: A Randomized Pilot Feasibility Study.

Jolana Wagner-Skacel, Sabrina Mörkl, Nina Dalkner, Frederike Fellendorf, Werner Fitz, Bianca Brix, Ruslan Neshev, Sarah Wedenig, Petra Mächler, Andreas Dorr and 9 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Jolana Wagner-SkacelDepartment of Medical Psychology and Psychotherapy, Medical University Graz, 8036 Graz, Austria.
Sabrina MörklDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0001-5034-6358
Nina DalknerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0001-7716-3674
Frederike FellendorfDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0001-7215-3848
Werner FitzDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Bianca BrixDepartment of Physiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, 8010 Graz, Austria.ORCID 0000-0002-7308-5450
Ruslan NeshevDepartment of Physiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, 8010 Graz, Austria.
Sarah WedenigDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Petra MächlerRehabilitation Center for Cardiovascular Disease, 8061 St. Radegund, Austria.
Andreas DorrRehabilitation Center for Cardiovascular Disease, 8061 St. Radegund, Austria.
Rainer PichaRehabilitation Center for Cardiovascular Disease, 8061 St. Radegund, Austria.
Maximilian E RudlofDepartment of Physiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, 8010 Graz, Austria.
Till O BartelDepartment of Physiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, 8010 Graz, Austria.
Josef M TatschlHealth Psychology Unit, Institute of Psychology, Karl-Franzens University of Graz, 8010 Graz, Austria.
Johanna M GostnerBiochemical Immunotoxicology Group, Institute of Medical Biochemistry, Medical University Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-1532-5177
Susanne A BengesserDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Eva Z ReininghausDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Josef JeneweinDepartment of Medical Psychology and Psychotherapy, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0003-4271-918X
Nandu GoswamiDepartment of Physiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, 8010 Graz, Austria.ORCID 0000-0002-6704-0723
Medical University of Graz · ATLudwig Boltzmann Institute for Arthritis and Rehabilitation · ATInnsbruck Medical University · ATUniversity of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multicomponent cardiac rehabilitation (CR) is a secondary prevention strategy for cardiac patients to tackle stress and psychosocial wellbeing. However, there is a lack of data on its psychoneuroimmunological effects and of biomarkers to determine individual risk and to develop treatment strategies. We conducted a pilot randomized controlled trial (RCT) to investigate the feasibility of deriving psychophysiological stress markers in patients with cardiovascular diseases. Thirty individuals with cardiovascular disease (mean age 58.8 years; 23.3% female) were enrolled and randomized into three treatment groups: standard rehabilitation, yoga, or transcendental meditation (TM). Depression, anxiety, sleep, stress perception, personality functioning, hair cortisol, serum tryptophan, kynurenine and neopterin concentrations were estimated at baseline and after a four-week intervention. Hair cortisol levels decreased significantly after rehabilitation in all groups

Indexed as

cardiovascular rehabilitationcortisolkynurenine totryptophan ratiopersonality functioningpsychosocial wellbeingsleep

Identifiers

PMID34573057
PMCPMC8467958
OpenAlexW3198395277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.