Evidence map›Paper›PMID 34573048›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Peroxiredoxin 6 Knockout Mice Demonstrate Anxiety Behavior and Attenuated Contextual Fear Memory after Receiving Acute Immobilization Stress.

Sarayut Phasuk, Peeraporn Varinthra, Andaman Nitjapol, Korakod Bandasak, Ingrid Y Liu

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. IRF8 deficiency causes anxiety-like behavior in a sex-dependent manner.bioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Behavioral and Synaptic Phenotypes of FemaleAntioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Sarayut PhasukInstitute of Medical Sciences, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0003-3862-7581
Peeraporn VarinthraInstitute of Medical Sciences, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0001-8070-5016
Andaman NitjapolFaculty of Medical Science, Naresuan University, Phitsanulok 65000, Thailand.ORCID 0000-0001-8760-3928
Korakod BandasakFaculty of Medical Science, Naresuan University, Phitsanulok 65000, Thailand.
Ingrid Y LiuInstitute of Medical Sciences, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0002-2795-2461
Naresuan University · THTzu Chi University · TWSiriraj Hospital · TH

Funding

Buddhist Tzu Chi Medical Foundation TCMF-SP-108-04Ministry of Science and Technology, Taiwan MOST-107-2410-H320-DOI-MY3
6 · The paper itself

Abstract

Stress can elicit glucocorticoid release to promote coping mechanisms and influence learning and memory performance. Individual memory performance varies in response to stress, and the underlying mechanism is not clear yet. Peroxiredoxin 6 (PRDX6) is a multifunctional enzyme participating in both physiological and pathological conditions. Several studies have demonstrated the correlation between PRDX6 expression level and stress-related disorders. Our recent finding indicates that lack of the

Indexed as

acute immobilization stressfear memoryglucocorticoidperoxiredoxin 6stress

Identifiers

PMID34573048
PMCPMC8466988
OpenAlexW3197120046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.