Evidence map›Paper›PMID 34572945›Full record

ArticleCancers2021

Reproducibility of mRNA-Based Testing of

Ramona Erber, Arndt Hartmann, Peter Andreas Fasching, Matthias Ruebner, Robert Stöhr, Matthias Wilhelm Beckmann, Miriam Zentgraf, Verena Popp, Jodi Weidler, Iris Simon and 15 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Evaluation ofCancers · 2023
    Article
  3. Article
  4. XPERTEcancermedicalscience · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 4 countries.

Ramona ErberInstitute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.ORCID 0000-0003-0315-1229
Arndt HartmannInstitute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Peter Andreas FaschingDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0003-4885-8471
Matthias RuebnerDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Robert StöhrInstitute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Matthias Wilhelm BeckmannDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Miriam ZentgrafInstitute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Verena PoppInstitute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Jodi WeidlerCepheid, Department of Medical and Scientific Affairs and Strategy, Oncology, 904 Caribbean Drive, Sunnyvale, CA 94089, USA.
Iris SimonCepheid, Department of Medical and Scientific Affairs and Strategy, Oncology, 904 Caribbean Drive, Sunnyvale, CA 94089, USA.
Steffi BeckerCepheid, Department of Medical and Scientific Affairs and Strategy, Oncology, 904 Caribbean Drive, Sunnyvale, CA 94089, USA.
Hanna HuebnerDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0001-6889-1493
Josephine FischerQualitätssicherungs-Initiative Pathologie QuIP GmbH, 10117 Berlin, Germany.
Elena Guerini RoccoDepartment of Pathology and Laboratory Medicine, IEO, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Giuseppe VialeDepartment of Pathology and Laboratory Medicine, IEO, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Anne CayreCentre Jean Perrin, Department of Pathology and Clermont Auvergne University, INSERM, U1240, "Imagerie Moléculaire et Stratégies Théranostiques", F-63011 Clermont Ferrand, France.
Frederique Penault-LlorcaCentre Jean Perrin, Department of Pathology and Clermont Auvergne University, INSERM, U1240, "Imagerie Moléculaire et Stratégies Théranostiques", F-63011 Clermont Ferrand, France.
Tamara Caniego CasasInstituto Ramón y Cajal de Investigación Sanitaria, 28034 Madrid, Spain.
Belén Pérez-MiésInstituto Ramón y Cajal de Investigación Sanitaria, 28034 Madrid, Spain.
José PalaciosInstituto Ramón y Cajal de Investigación Sanitaria, 28034 Madrid, Spain.ORCID 0000-0002-6730-5066
Paul JankInstitute of Pathology, UKGM-University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Germany.ORCID 0000-0001-7076-0476
Carsten DenkertInstitute of Pathology, UKGM-University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Germany.
Lina KhouryMVZ Helios Hospital Emil von Behring GmbH, 14165 Berlin, Germany.
Thomas MairingerMVZ Helios Hospital Emil von Behring GmbH, 14165 Berlin, Germany.
Fulvia FerrazziInstitute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.ORCID 0000-0003-4011-4638
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEHelios Klinikum Emil von Behring · DEInserm · FRPhilipps University of Marburg · DEUniversidad de Alcalá · ESUniversity of Milan · ITInstituto de Salud Carlos III · ESZentrum für Qualität in der Pflege · DE

Funding

Cepheid not applicable
6 · The paper itself

Abstract

Estrogen receptor (ER), progesterone receptor (PgR), Ki-67, and HER2 immunohistochemistry (IHC) together with

Indexed as

breast cancerERBB2ESR1GeneXpertMKI67mRNA expression testingPGRSTRAT4Xpert

Identifiers

PMID34572945
PMCPMC8470348
OpenAlexW3201043281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.