Evidence map›Paper›PMID 34572909›Full record

ReviewCancers2021

The Multiple Faces of MNT and Its Role as a MYC Modulator.

Judit Liaño-Pons, Marie Arsenian-Henriksson, Javier León

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. MNT: a new target for AML.Blood neoplasia · 2025
    Article
  2. Identification of dynamic network biomarkerMolecular therapy. Oncology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer.Current issues in molecular biology · 2023
    Review
  8. The Myc-Like Mlx Network Impacts Aging and Metabolism.bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Review
  11. FTO Alleviates CdClInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Judit Liaño-PonsDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, SE-171 65 Stockholm, Sweden.ORCID 0000-0001-8097-4750
Marie Arsenian-HenrikssonDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, SE-171 65 Stockholm, Sweden.
Javier LeónDepartmento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC), Universidad de Cantabria-CSIC, 39011 Santander, Spain.ORCID 0000-0001-5803-0112
Karolinska Institutet · SEUniversidad de Cantabria · ES

Funding

Agencia Estatal de Investigación SAF2017-88026-RRadiumhemmet Research Fund, Sweden 191073Swedish Cancer Society 19 0510PjSwedish Childhood Cancer Fund PR 2018-0026Swedish Research Council 2018-02580
6 · The paper itself

Abstract

MNT is a crucial modulator of MYC, controls several cellular functions, and is activated in most human cancers. It is the largest, most divergent, and most ubiquitously expressed protein of the MXD family. MNT was first described as a MYC antagonist and tumor suppressor. Indeed, 10% of human tumors present deletions of one

Indexed as

cancerMAXMNTMYCproliferationRELtranscriptional regulation

Identifiers

PMID34572909
PMCPMC8465425
OpenAlexW3199810721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.