Evidence map›Paper›PMID 34572819›Full record

ArticleCancers2021

Hyperspectral Imaging Combined with Artificial Intelligence in the Early Detection of Esophageal Cancer.

Cho-Lun Tsai, Arvind Mukundan, Chen-Shuan Chung, Yi-Hsun Chen, Yao-Kuang Wang, Tsung-Hsien Chen, Yu-Sheng Tseng, Chien-Wei Huang, I-Chen Wu, Hsiang-Chen Wang

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Clinical applications of hyperspectral imaging in gastroenterology and hepatology: A systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
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  8. Review
  9. Classification of esophageal cancer by using hyperspectral data.International journal of computer assisted radiology and surgery · 2026
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  20. Precision Imaging for Early Detection of Esophageal Cancer.Bioengineering (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Cho-Lun TsaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chia Yi City 60002, Taiwan.
Arvind MukundanDepartment of Mechanical Engineering, Advanced Institute of Manufacturing with High tech Innovations (AIM-HI) and Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, 168, University Rd., Min Hsiung, Chia Yi County 62102, Taiwan.ORCID 0000-0002-7741-3722
Chen-Shuan ChungDepartment of Internal Medicine, Far Eastern Memorial Hospital, No.21, Sec. 2, Nanya S. Rd., Banciao Dist., New Taipei City 22060, Taiwan.ORCID 0000-0001-9224-4958
Yi-Hsun ChenDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chia Yi City 60002, Taiwan.ORCID 0000-0001-9981-5143
Yao-Kuang WangDivision of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1st Rd., Sanmin Dist., Kaohsiung City 80756, Taiwan.
Tsung-Hsien ChenDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chia Yi City 60002, Taiwan.ORCID 0000-0002-1542-1495
Yu-Sheng TsengDepartment of Mechanical Engineering, Advanced Institute of Manufacturing with High tech Innovations (AIM-HI) and Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, 168, University Rd., Min Hsiung, Chia Yi County 62102, Taiwan.
Chien-Wei HuangDepartment of Gastroenterology, Kaohsiung Armed Forces General Hospital, 2, Zhongzheng 1st. Rd., Lingya District, Kaohsiung City 80284, Taiwan.
I-Chen WuDivision of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1st Rd., Sanmin Dist., Kaohsiung City 80756, Taiwan.ORCID 0000-0002-6260-0402
Hsiang-Chen WangDepartment of Mechanical Engineering, Advanced Institute of Manufacturing with High tech Innovations (AIM-HI) and Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, 168, University Rd., Min Hsiung, Chia Yi County 62102, Taiwan.ORCID 0000-0003-4107-2062
Chia-Yi Christian Hospital · TWNational Chung Cheng University · TWKaohsiung Medical University · TWFar Eastern Memorial Hospital · TWTajen University · TW

Funding

Ditmanson Medical Foundation Chia-Yi Christian Hospital Research Program R110-27Kaohsiung Armed Forces General Hospital research project 109-002Ministry of Science and Technology, Taiwan MOST 105-2923-E-194-003 MY3, 108-2823-8-194-002, 109-2622-8-194-001- TE1, and 109-2622-8-194-007
6 · The paper itself

Abstract

This study uses hyperspectral imaging (HSI) and a deep learning diagnosis model that can identify the stage of esophageal cancer and mark the locations. This model simulates the spectrum data from the image using an algorithm developed in this study which is combined with deep learning for the classification and diagnosis of esophageal cancer using a single-shot multibox detector (SSD)-based identification system. Some 155 white-light endoscopic images and 153 narrow-band endoscopic images of esophageal cancer were used to evaluate the prediction model. The algorithm took 19 s to predict the results of 308 test images and the accuracy of the test results of the WLI and NBI esophageal cancer was 88 and 91%, respectively, when using the spectral data. Compared with RGB images, the accuracy of the WLI was 83% and the NBI was 86%. In this study, the accuracy of the WLI and NBI was increased by 5%, confirming that the prediction accuracy of the HSI detection method is significantly improved.

Indexed as

hyperspectral imagingnarrow-band endoscopy and dysplasiasingle-shot multibox detectorwhite-light endoscopy

Identifiers

PMID34572819
PMCPMC8469506
OpenAlexW3199596098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.