Evidence map›Paper›PMID 34572812›Full record

ArticleCancers2021

Mutations in Epigenetic Regulation Genes in Gastric Cancer.

Marina V Nemtsova, Alexey I Kalinkin, Ekaterina B Kuznetsova, Irina V Bure, Ekaterina A Alekseeva, Igor I Bykov, Tatiana V Khorobrykh, Dmitry S Mikhaylenko, Alexander S Tanas, Vladimir V Strelnikov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Marina V NemtsovaLaboratory of Medical Genetics, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Alexey I KalinkinLaboratory of Epigenetics, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0001-9215-4581
Ekaterina B KuznetsovaLaboratory of Medical Genetics, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Irina V BureLaboratory of Medical Genetics, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Ekaterina A AlekseevaLaboratory of Medical Genetics, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Igor I BykovDepartment No. 1, Medical Faculty, Faculty Surgery, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Tatiana V KhorobrykhDepartment No. 1, Medical Faculty, Faculty Surgery, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Dmitry S MikhaylenkoLaboratory of Medical Genetics, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0001-9780-8708
Alexander S TanasLaboratory of Epigenetics, Research Centre for Medical Genetics, 115522 Moscow, Russia.
Vladimir V StrelnikovLaboratory of Epigenetics, Research Centre for Medical Genetics, 115522 Moscow, Russia.ORCID 0000-0001-9283-902X
Sechenov University · RUResearch Centre for Medical Genetics · RU

Funding

Ministry of Science and Higher Education of the Russian Federation RCMGRussian Foundation for Basic Research 18-29-09020
6 · The paper itself

Abstract

We have performed mutational profiling of 25 genes involved in epigenetic processes on 135 gastric cancer (GC) samples. In total, we identified 79 somatic mutations in 49/135 (36%) samples. The minority (

Indexed as

epigenetic regulation genesgastric cancermolecular genetic markerssomatic mutations

Identifiers

PMID34572812
PMCPMC8467700
OpenAlexW3200245328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.