Evidence map›Paper›PMID 34572790›Full record

ArticleCancers2021

Cyano- and Ketone-Containing Selenoesters as Multi-Target Compounds against Resistant Cancers.

Nikoletta Szemerédi, Simona Dobiasová, Noemi Salardón-Jiménez, Annamária Kincses, Márta Nové, Giyaullah Habibullah, Clotilde Sevilla-Hernández, Miguel Benito-Lama, Francisco-Javier Alonso-Martínez, Jitka Viktorová and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Selenium-Containing Compounds in Breast Cancer Therapy.Biological trace element research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Nikoletta SzemerédiDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Faculty of Medicine, University of Szeged, Semmelweis utca 6, 6725 Szeged, Hungary.ORCID 0000-0002-8638-5815
Simona DobiasováDepartment of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague 6, Czech Republic.
Noemi Salardón-JiménezInstituto de Química Orgánica General (IQOG-CSIC), Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-2215-804X
Annamária KincsesDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Faculty of Medicine, University of Szeged, Semmelweis utca 6, 6725 Szeged, Hungary.ORCID 0000-0002-1591-1419
Márta NovéDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Faculty of Medicine, University of Szeged, Semmelweis utca 6, 6725 Szeged, Hungary.
Giyaullah HabibullahDepartment of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague 6, Czech Republic.ORCID 0000-0001-9455-655X
Clotilde Sevilla-HernándezInstituto de Química Orgánica General (IQOG-CSIC), Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-0745-5281
Miguel Benito-LamaInstituto de Química Orgánica General (IQOG-CSIC), Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain.
Francisco-Javier Alonso-MartínezInstituto de Química Orgánica General (IQOG-CSIC), Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain.
Jitka ViktorováDepartment of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague 6, Czech Republic.ORCID 0000-0003-0857-153X
Gabriella SpenglerDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Faculty of Medicine, University of Szeged, Semmelweis utca 6, 6725 Szeged, Hungary.ORCID 0000-0001-8085-0950
Enrique Domínguez-ÁlvarezInstituto de Química Orgánica General (IQOG-CSIC), Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0003-2655-1575
Consejo Superior de Investigaciones Científicas · ESUniversity of Szeged · HUUniversity of Chemistry and Technology, Prague · CZ

Funding

Consejo Superior de Investigaciones Científicas LINKA20285COST Action 17104Czech Ministry of Education, Youth and Sports LTC19007International Visegrad Fund 22010090University of Szeged GINOP-2.3.2-15-2016-00038University of Szeged SZTE ÁOK-KKA 2018/270-62-2
6 · The paper itself

Abstract

Fifteen selenocompounds, comprising of eight ketone-containing selenoesters (

Indexed as

ABCB1apoptosiscancerefflux pumpmultidrug resistanceselenium

Identifiers

PMID34572790
PMCPMC8465942
OpenAlexW3201033710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.