Evidence map›Paper›PMID 34572780›Full record

ArticleCancers2021

Genomic Characterization and Therapeutic Targeting of HPV Undetected Cervical Carcinomas.

Fiona J Ruiz, Aishwarya Sundaresan, Jin Zhang, Chandra S Pedamallu, Mari K Halle, Vinodh Srinivasasainagendra, Jianqing Zhang, Naoshad Muhammad, Jennifer Stanley, Stephanie Markovina and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Cervical HPV-independent adenosquamous carcinoma: report of a case series.Virchows Archiv : an international journal of pathology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Fiona J RuizDivision of Biological and Biomedical Sciences Molecular Cell Biology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Aishwarya SundaresanDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jin ZhangDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Chandra S PedamalluDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-7899-0206
Mari K HalleDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-2660-8271
Vinodh SrinivasasainagendraDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jianqing ZhangDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Naoshad MuhammadDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Jennifer StanleyDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Stephanie MarkovinaDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Hemant K TiwariDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Perry W GrigsbyDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Camilla KrakstadDepartment of Obstetrics and Gynaecology, Haukeland University Hospital, 5021 Bergen, Norway.ORCID 0000-0002-0174-8139
Julie K SchwarzDivision of Biological and Biomedical Sciences Molecular Cell Biology, Washington University School of Medicine, St. Louis, MO 63108, USA.
Akinyemi I OjesinaDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Washington University in St. Louis · USUniversity of Alabama at Birmingham · USHaukeland University Hospital · NO

Funding

MOLECULAR ONCOLOGY TRAINING GRANTT32CA113275 · NCI · WASHINGTON UNIVERSITY · PI Matthew J Walter · 2006 to 2026
$5.7M
Optimizing radiation therapy through the manipulation of glutamine metabolismR01CA181745 · NCI · WASHINGTON UNIVERSITY · PI SCHWARZ, JULIE KRISTINA · 2014 to 2025
$3.4M
Mechanisms of radiation-induced tumor cell death and survival in cervical cancerK08CA237822 · NCI · WASHINGTON UNIVERSITY · PI MARKOVINA, STEPHANIE · 2019 to 2023
$1.1M
HPV alternative splicing in cervical cancer radiation responseK22CA237839 · NCI · WASHINGTON UNIVERSITY · PI ZHANG, JIN · 2021 to 2023
$460k
HelseVest 912227NCI NIH HHS K22 CA237839NCI NIH HHS R01 CA181745NIH HHS K08CA237822NIH HHS K22CA237839NIH HHS R01CA181745NIH HHS T32 CA113275Norwegian Research Council 273280V Foundation DVP2018-007V Foundation V2015-009
6 · The paper itself

Abstract

Cervical cancer tumors with undetectable HPV (HPV

Indexed as

cervixHPVpalbociclib

Identifiers

PMID34572780
PMCPMC8467954
OpenAlexW3199398385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.