Evidence map›Paper›PMID 34572741›Full record

ArticleCancers2021

Transcriptome of Male Breast Cancer Matched with Germline Profiling Reveals Novel Molecular Subtypes with Possible Clinical Relevance.

Veronica Zelli, Valentina Silvestri, Virginia Valentini, Agostino Bucalo, Piera Rizzolo, Ines Zanna, Simonetta Bianchi, Anna Coppa, Giuseppe Giannini, Laura Cortesi and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. The Oncotype DX® 21-gene recurrence score and clinical outcomes in hormone receptor-positive, HER2-negative male breast cancer: a scoping review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Exploring the One Health Paradigm in Male Breast Cancer.Journal of mammary gland biology and neoplasia · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Veronica ZelliDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Valentina SilvestriDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0712-9379
Virginia ValentiniDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Agostino BucaloDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Piera RizzoloDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Ines ZannaCancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 08518 Florence, Italy.ORCID 0000-0002-5710-6506
Simonetta BianchiDivision of Pathological Anatomy, Department of Health Sciences, University of Florence, 08518 Florence, Italy.ORCID 0000-0002-2605-4758
Anna CoppaDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-9758-5444
Giuseppe GianniniDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0299-4056
Laura CortesiDepartment of Oncology and Haematology, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0001-8950-8561
Daniele CalistriIRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0002-5064-2023
Maria Grazia TibilettiDepartment of Pathology, ASST Settelaghi and Centro di Ricerca per lo Studio dei Tumori Eredo-Familiari, Università dell'Insubria, 21100 Varese, Italy.
Stephen B FoxDepartment of Pathology, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC 3000, Australia.
kCon FabSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.
Domenico PalliCancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 08518 Florence, Italy.ORCID 0000-0002-5558-2437
Laura OttiniDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Sapienza University of Rome · ITThe University of Melbourne · AUIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITUniversity of Florence · ITUniversity of Insubria · ITUniversity of Modena and Reggio Emilia · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG2018-21389Lega italiana per la lotta contro i tumori (LILT) IG2019Ministero dell'Istruzione, dell'Università e della Ricerca Dipartimenti di Eccellenza-L. 232/2016
6 · The paper itself

Abstract

Male breast cancer (MBC) is a rare and understudied disease compared with female BC. About 15% of MBCs are associated with germline mutation in BC susceptibility genes, mainly

Indexed as

BRCA1/2germline mutationsmale breast cancermolecular subtypestranscriptome profiling

Identifiers

PMID34572741
PMCPMC8469418
OpenAlexW3197841206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.