Evidence map›Paper›PMID 34572657›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Efflux Pump Inhibition and Resistance Modulation in

Katarina Šimunović, Julia Solnier, Fabian Alperth, Olaf Kunert, Sonja Smole Možina, Franz Bucar

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Unveiling the Pharmacognostic Potential ofPlants (Basel, Switzerland) · 2025
    Article
  4. Ultrasound-assisted extraction ofFrontiers in pharmacology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Katarina ŠimunovićDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, University of Graz, Beethovenstraße 8, 8010 Graz, Austria.
Julia SolnierDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, University of Graz, Beethovenstraße 8, 8010 Graz, Austria.ORCID 0000-0003-2784-1435
Fabian AlperthDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, University of Graz, Beethovenstraße 8, 8010 Graz, Austria.
Olaf KunertDepartment of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences, University of Graz, Beethovenstraße 8, 8010 Graz, Austria.
Sonja Smole MožinaDepartment of Food Science and Technology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7949-8128
Franz BucarDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, University of Graz, Beethovenstraße 8, 8010 Graz, Austria.ORCID 0000-0002-7417-616X
University of Graz · ATUniversity of Ljubljana · SI

Funding

CEEPUS not availableGoStyria not availableJavna Agencija za Raziskovalno Dejavnost RS P4-0116Karl-Franzens-Universität Graz not available
6 · The paper itself

Abstract

Antibiotic resistance is a growing problem and may become the next major global health crisis if no timely actions are taken. Mycobacterial infections are widespread and, due to antibiotic resistance, also hard to treat and a major cause of mortality. Natural compounds have the potential to increase antibiotic effectiveness due to their resistance modulatory and antimicrobial effects. In this study,

Indexed as

antibacterialefflux pump inhibitorethidium bromide accumulationimperatorinMycobacterium smegmatisostruthinPeucedanum ostruthiumresistance modulation

Identifiers

PMID34572657
PMCPMC8472667
OpenAlexW3196803737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.