Evidence map›Paper›PMID 34572650›Full record

ReviewAntibiotics (Basel, Switzerland)2021

How Do We Determine the Efficacy of an Antibacterial Surface? A Review of Standardised Antibacterial Material Testing Methods.

Alexander J Cunliffe, Peter D Askew, Ina Stephan, Gillian Iredale, Patrick Cosemans, Lisa M Simmons, Joanna Verran, James Redfern

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
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  9. Ethnomedicinal uses, phytochemistry, and biological properties ofJournal of traditional and complementary medicine · 2026
    Review
  10. Article
  11. Article
  12. Bacteriophage-Based Control of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  13. Article
  14. Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alexander J CunliffeDepartment of Natural Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.
Peter D Askew(Industrial Microbiological Services Ltd.) IMSL, Pale Lane, Hartley Whitney, Hants RG27 8DH, UK.
Ina Stephan(Bundesanstalt für Materialforschung und -prüfung) BAM, Unter den Eichen 87, 12205 Berlin, Germany.
Gillian Iredale(Industrial Microbiological Services Ltd.) IMSL, Pale Lane, Hartley Whitney, Hants RG27 8DH, UK.
Patrick CosemansSirris, Wetenschapspark 3, B-3590 Diepenbeek, Belgium.
Lisa M SimmonsDepartment of Engineering, Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.
Joanna VerranDepartment of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.ORCID 0000-0002-5539-6896
James RedfernDepartment of Natural Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.ORCID 0000-0003-0958-683X
Manchester Metropolitan University · GBFederal Institute For Materials Research and Testing · DESirris · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Materials that confer antimicrobial activity, be that by innate property, leaching of biocides or design features (e.g., non-adhesive materials) continue to gain popularity to combat the increasing and varied threats from microorganisms, e.g., replacing inert surfaces in hospitals with copper. To understand how efficacious these materials are at controlling microorganisms, data is usually collected via a standardised test method. However, standardised test methods vary, and often the characteristics and methodological choices can make it difficult to infer that any perceived antimicrobial activity demonstrated in the laboratory can be confidently assumed to an end-use setting. This review provides a critical analysis of standardised methodology used in academia and industry, and demonstrates how many key methodological choices (e.g., temperature, humidity/moisture, airflow, surface topography) may impact efficacy assessment, highlighting the need to carefully consider intended antimicrobial end-use of any product.

Indexed as

22196antibacterial coatingsantimicrobial materialsantimicrobial surfacesantimicrobial testing

Identifiers

PMID34572650
PMCPMC8472414
OpenAlexW3197550346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.