Evidence map›Paper›PMID 34572609›Full record

ReviewAntibiotics (Basel, Switzerland)2021

The Accuracy of Molecular Detection Targeting the Mutation C2611T for Detecting Moderate-Level Azithromycin Resistance in

Qian Zhou, Jingwei Liu, Shaochun Chen, Wenqi Xu, Yan Han, Yueping Yin

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Heterogeneity of azithromycin resistance markers inNew microbes and new infections · 2026
    Review
  3. Article
  4. Evaluation of the Allplex NG & DR assay for molecular prediction of ciprofloxacin and azithromycin resistance in Neisseria gonorrhoeae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  5. Article
  6. Article
  7. Antibiotic Resistance inMicroorganisms · 2022
    Article
  8. Evaluation ofInfection and drug resistance · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qian ZhouNational Center for STD Control, Chinese Center for Disease Control and Prevention, Department of Reference STD Lab, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China.ORCID 0000-0002-0712-1062
Jingwei LiuNational Center for STD Control, Chinese Center for Disease Control and Prevention, Department of Reference STD Lab, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China.ORCID 0000-0001-7260-141X
Shaochun ChenNational Center for STD Control, Chinese Center for Disease Control and Prevention, Department of Reference STD Lab, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China.
Wenqi XuNational Center for STD Control, Chinese Center for Disease Control and Prevention, Department of Reference STD Lab, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China.
Yan HanNational Center for STD Control, Chinese Center for Disease Control and Prevention, Department of Reference STD Lab, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China.
Yueping YinNational Center for STD Control, Chinese Center for Disease Control and Prevention, Department of Reference STD Lab, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

National Clinical Research Center 2019060001
6 · The paper itself

Abstract

backgroundMETHODS AND

findingsIn this systematic review and meta-analysis, two researchers independently searched six databases for studies with data for the azithromycin minimum inhibitory concentrations (MICs) and the 23S rRNA mutation C2611T of each

conclusionThrough this meta-analysis, we found that the C2611T mutation of 23S rRNA is valuable for the molecular diagnostic of moderate-level azithromycin resistance (ML-AzmR) in

Indexed as

23S rRNAazithromycin resistanceNeisseria gonorrhoeae

Identifiers

PMID34572609
PMCPMC8471969
OpenAlexW3195129276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.