Evidence map›Paper›PMID 34572591›Full record

ArticleBiomolecules2021

Prognostic Impact of Genetic Variants of MECP2 and TIRAP on Clinical Outcomes of Systemic Lupus Erythematosus with and without Nephritis.

Safaa I Tayel, Nashwa M Muharram, Dina S Fotoh, Hany S Elbarbary, Huda I Abd-Elhafiz, Eman A El-Masry, Ahmed E Taha, Shimaa E Soliman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Safaa I TayelMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Menoufia University, Shebin el Kom 32511, Egypt.ORCID 0000-0002-6528-0256
Nashwa M MuharramMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Menoufia University, Shebin el Kom 32511, Egypt.
Dina S FotohPhysical Medicine, Rheumatology and Rehabilitation Department, Faculty of Medicine, Menoufia University, Shebin el Kom 32511, Egypt.
Hany S ElbarbaryRenal Unit, Department of Internal Medicine, Faculty of Medicine, Menoufia University, Shebin el Kom 32511, Egypt.
Huda I Abd-ElhafizClinical Pharmacology Department, Faculty of Medicine, Menoufia University, Shebin el Kom 32511, Egypt.
Eman A El-MasryMicrobiology and Immunology Unit, Department of Pathology, College of Medicine, Jouf University, Sakaka 72388, Saudi Arabia.
Ahmed E TahaMicrobiology and Immunology Unit, Department of Pathology, College of Medicine, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0002-5766-4495
Shimaa E SolimanMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Menoufia University, Shebin el Kom 32511, Egypt.
Al Baha University · SAMenoufia University · EGJouf University · SAKing Faisal University · SAMansoura University · EGQassim University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune illness with a growing prevalence in many populations. Few studies have examined genetic predisposition to SLE, so we aimed to examine the clinical impact of the genetic polymorphisms

Indexed as

Genetic Predisposition to DiseaseGenetic VariationAdultBlood SedimentationFemaleHumansLupus NephritisMembrane GlycoproteinsMethyl-CpG-Binding Protein 2Polymorphism, Single NucleotidePrognosisReceptors, Interleukin-1Treatment OutcomeMECP2 protein, humanMembrane GlycoproteinsMethyl-CpG-Binding Protein 2Receptors, Interleukin-1TIRAP protein, humanarthritisMECPnephritissystemic lupus erythematosusTIRAP

Identifiers

PMID34572591
PMCPMC8466489
OpenAlexW3199688591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.