Evidence map›Paper›PMID 34572543›Full record

ArticleBiomolecules2021

The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite.

André Luís Condeles, José Carlos Toledo Junior

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Insights on the endogenous labile iron pool binding properties.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

André Luís CondelesDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-901, Brazil.ORCID 0000-0002-7511-1077
José Carlos Toledo JuniorDepartamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-901, Brazil.ORCID 0000-0003-0818-0846
Universidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While investigating peroxynitrite-dependent oxidation in murine RAW 264.7 macrophage cells, we observed that removal of the Labile Iron Pool (LIP) by chelation increases the intracellular oxidation of the fluorescent indicator H

Indexed as

AldehydesAnimalsCatalysisFluoresceinsFluorescenceHydrazonesIronIron Chelating AgentsIsoindolesKineticsMiceModels, BiologicalNitric Oxide DonorsOrganoselenium CompoundsOxidation-ReductionParaquat2',7'-dichlorodihydrofluorescein diacetateAldehydesebselenFluoresceinsHydrazonesIronIron Chelating AgentsIsoindolesNitric Oxide DonorsOrganoselenium CompoundsParaquatPeroxynitrous Acidsalicylaldehyde isonicotinoyl hydrazonelabile iron poolnitric oxidenitrogen dioxideoxidative stressperoxynitritesuperoxide

Identifiers

PMID34572543
PMCPMC8466499
OpenAlexW3196355301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.