ArticleBiomolecules2021
3D-Printed Coronary Plaques to Simulate High Calcification in the Coronary Arteries for Investigation of Blooming Artifacts.
Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- In-vitro Detection of Intramammary-like Macrocalcifications Using Susceptibility-weighted MR Imaging Techniques at 1.5T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Cardiovascular computed tomography in cardiovascular disease: An overview of its applications from diagnosis to prediction.Journal of geriatric cardiology : JGC · 2024Article
- Biomimicking Atherosclerotic Vessels: A Relevant and (Yet) Sub-Explored Topic.Biomimetics (Basel, Switzerland) · 2024Review
- Cardiovascular Computed Tomography in the Diagnosis of Cardiovascular Disease: Beyond Lumen Assessment.Journal of cardiovascular development and disease · 2024Review
- Comparative Study of Plan Robustness for Breast Radiotherapy: Volumetric Modulated Arc Therapy Plans with Robust Optimization versus Manual Flash Approach.Diagnostics (Basel, Switzerland) · 2023Article
- Three-Dimensional Bioprinting in Cardiovascular Disease: Current Status and Future Directions.Biomolecules · 2023Review
- Diagnostic Performance of Artificial Intelligence-Based Computer-Aided Detection and Diagnosis in Pediatric Radiology: A Systematic Review.Children (Basel, Switzerland) · 2023Review
- Patient-Specific 3D-Printed Low-Cost Models in Medical Education and Clinical Practice.Micromachines · 2023Review
- Medical Fuzzy-Expert System for Assessment of the Degree of Anatomical Lesion of Coronary Arteries.International journal of environmental research and public health · 2023Article
- 3D Printed Models in Cardiovascular Disease: An Exciting Future to Deliver Personalized Medicine.Micromachines · 2022Review
- Artificial Intelligence for Radiation Dose Optimization in Pediatric Radiology: A Systematic Review.Children (Basel, Switzerland) · 2022Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnostic value of coronary computed tomography angiography (CCTA) is significantly affected by high calcification in the coronary arteries owing to blooming artifacts limiting its accuracy in assessing the calcified plaques. This study aimed to simulate highly calcified plaques in 3D-printed coronary models. A combination of silicone + 32.8% calcium carbonate was found to produce 800 HU, representing extensive calcification. Six patient-specific coronary artery models were printed using the photosensitive polyurethane resin and a total of 22 calcified plaques with diameters ranging from 1 to 4 mm were inserted into different segments of these 3D-printed coronary models. The coronary models were scanned on a 192-slice CT scanner with 70 kV, pitch of 1.4, and slice thickness of 1 mm. Plaque attenuation was measured between 1100 and 1400 HU. Both maximum-intensity projection (MIP) and volume rendering (VR) images (wide and narrow window widths) were generated for measuring the diameters of these calcified plaques. An overestimation of plaque diameters was noticed on both MIP and VR images, with measurements on the MIP images close to those of the actual plaque sizes (<10% deviation), and a large measurement discrepancy observed on the VR images (up to 50% overestimation). This study proves the feasibility of simulating extensive calcification in coronary arteries using a 3D printing technique to develop calcified plaques and generate 3D-printed coronary models.
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