Evidence map›Paper›PMID 34572519›Full record

ArticleBiomolecules2021

A Dendritic Cell-Activating Rv1876 Protein Elicits Mycobacterium Bovis BCG-Prime Effect via Th1-Immune Response.

Seunga Choi, Han-Gyu Choi, Yong Woo Back, Hye-Soo Park, Kang-In Lee, Sintayehu Kebede Gurmessa, Thuy An Pham, Hwa-Jung Kim

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Seunga ChoiDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.ORCID 0000-0002-6688-8239
Han-Gyu ChoiDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Yong Woo BackDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Hye-Soo ParkDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kang-In LeeDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Sintayehu Kebede GurmessaDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.ORCID 0000-0003-1644-2359
Thuy An PhamDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Hwa-Jung KimDepartment of Microbiology, College of Medicine, Chungnam National University, Daejeon 35015, Korea.ORCID 0000-0002-1127-0909
Chungnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widely administered tuberculosis (TB) vaccine, Bacillus Calmette-Guerin (BCG), is the only licensed vaccine, but has highly variable efficiency against childhood and pulmonary TB. Therefore, the BCG prime-boost strategy is a rational solution for the development of new TB vaccines. Studies have shown that

Indexed as

ImmunityAnimalsAntigens, BacterialBacterial ProteinsCell ProliferationCytokinesDendritic CellsFemaleImmunologic MemoryLymphocyte ActivationMiceMice, Inbred C57BLMutationMycobacterium bovisTh1 CellsVaccinationAntigens, BacterialBacterial ProteinsCytokinesBCG-prime boostdendritic cellmycobacterium tuberculosisRv1876Th1 polarization

Identifiers

PMID34572519
PMCPMC8465531
OpenAlexW3198448590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.