Evidence map›Paper›PMID 34572512›Full record

ArticleBiomolecules2021

Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket.

Christoph Grininger, Mario Leypold, Philipp Aschauer, Tea Pavkov-Keller, Lina Riegler-Berket, Rolf Breinbauer, Monika Oberer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Virulence Factors inBiomolecules · 2023
    Article
  4. The cause-effect relation of tuberculosis on incidence of diabetes mellitus.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christoph GriningerInstitute of Molecular Biosciences, University of Graz, 8010 Graz, Austria.ORCID 0000-0002-1154-4244
Mario LeypoldInstitute of Organic Chemistry, Graz University of Technology, 8010 Graz, Austria.ORCID 0000-0002-9780-6371
Philipp AschauerInstitute of Molecular Biosciences, University of Graz, 8010 Graz, Austria.
Tea Pavkov-KellerInstitute of Molecular Biosciences, University of Graz, 8010 Graz, Austria.ORCID 0000-0001-7871-6680
Lina Riegler-BerketInstitute of Molecular Biosciences, University of Graz, 8010 Graz, Austria.
Rolf BreinbauerInstitute of Organic Chemistry, Graz University of Technology, 8010 Graz, Austria.ORCID 0000-0001-6009-7359
Monika ObererInstitute of Molecular Biosciences, University of Graz, 8010 Graz, Austria.ORCID 0000-0003-2525-9513
University of Graz · ATGraz University of Technology · AT

Funding

Austrian Science Fund FWF DOC 130Austrian Science Fund FWF DOC 50Austrian Science Fund FWF P 24857Austrian Science Fund FWF P 29432
6 · The paper itself

Abstract

Tuberculosis continues to be a major threat to the human population. Global efforts to eradicate the disease are ongoing but are hampered by the increasing occurrence of multidrug-resistant strains of

Indexed as

Binding SitesCrystallography, X-RayEntropyModels, MolecularMonoacylglycerol LipasesMutationMycobacterium tuberculosisSubstrate SpecificitySurface PropertiesMonoacylglycerol Lipasesconformational changecovalent inhibitorslipasemonoacylglycerol lipaseMycobacterium tuberculosisRv0183X-ray crystallography

Identifiers

PMID34572512
PMCPMC8472722
OpenAlexW3197144086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.