Evidence map›Paper›PMID 34572509›Full record

ArticleBiomolecules2021

Adropin Serum Levels in Patients with Primary Sjögren's Syndrome.

Marijana Janković Danolić, Dijana Perković, Marin Petrić, Igor Barišić, Katarina Gugo, Joško Božić

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marijana Janković DanolićSchool of Medicine, University of Split, 21000 Split, Croatia.
Dijana PerkovićDepartment of Internal Medicine, Division of Clinical Immunology and Rheumatology, University Hospital of Split, 21000 Split, Croatia.
Marin PetrićDepartment of Internal Medicine, Division of Clinical Immunology and Rheumatology, University Hospital of Split, 21000 Split, Croatia.
Igor BarišićDepartment of Diagnostic and Interventional Radiology, University Hospital of Split, 21000 Split, Croatia.
Katarina GugoDepartment of Medical Laboratory Diagnostics, University Hospital of Split, 21000 Split, Croatia.
Joško BožićDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-1634-0635
University of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary Sjögren's syndrome (pSS) patients have higher prevalence of endothelial dysfunction and premature atherosclerosis. Recent studies investigated adropin, a secretory protein that can regulate lipid metabolism and insulin resistance and protect endothelial cells' function and that has an anti-inflammatory effect. The aim of this study was to determine adropin levels in pSS patients compared to healthy controls. Additional goals were exploring the correlation between adropin and several metabolic and immunological parameters in pSS, including disease specific antibodies, EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI), and Sjögren's Syndrome Disease Damage Index (SSDDI). This research included 52 pSS patients and 52 healthy controls. pSS patients have significantly higher adropin levels compared to the control group (3.76 ± 0.68 vs. 3.14 ± 0.69 ng/mL,

Indexed as

Case-Control StudiesFemaleHumansIntercellular Signaling Peptides and ProteinsLinear ModelsMaleMiddle AgedSjogren's SyndromeEnho protein, humanIntercellular Signaling Peptides and Proteinsadropinanti SSA/Ro52 antibodiesendothelial dysfunctionprimary Sjögren’s syndromeSSDDI

Identifiers

PMID34572509
PMCPMC8466460
OpenAlexW3197388341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.