Evidence map›Paper›PMID 34572443›Full record

ReviewBiomedicines2021

Multi-Modal Biological Destruction by Cold Atmospheric Plasma: Capability and Mechanism.

Dayun Yan, Alisa Malyavko, Qihui Wang, Kostya Ken Ostrikov, Jonathan H Sherman, Michael Keidar

Abstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dayun YanDepartment of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA.ORCID 0000-0002-9801-021X
Alisa MalyavkoSchool of Medicine and Health Science, George Washington University, Washington, DC 20052, USA.ORCID 0000-0002-1515-1843
Qihui WangDepartment of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA.
Kostya Ken OstrikovSchool of Chemistry and Physics, Queensland University of Technology (QUT), Brisbane, QLD 4000, Australia.
Jonathan H ShermanWVU Medicine-Berkeley Medical Center, West Virginia University, Martinsburg, WV 25401, USA.
Michael KeidarDepartment of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA.ORCID 0000-0003-0869-4310

Funding

National Science Foundation 1747760
6 · The paper itself

Abstract

Cold atmospheric plasma (CAP) is a near-room-temperature, partially ionized gas composed of reactive neutral and charged species. CAP also generates physical factors, including ultraviolet (UV) radiation and thermal and electromagnetic (EM) effects. Studies over the past decade demonstrated that CAP could effectively induce death in a wide range of cell types, from mammalian to bacterial cells. Viruses can also be inactivated by a CAP treatment. The CAP-triggered cell-death types mainly include apoptosis, necrosis, and autophagy-associated cell death. Cell death and virus inactivation triggered by CAP are the foundation of the emerging medical applications of CAP, including cancer therapy, sterilization, and wound healing. Here, we systematically analyze the entire picture of multi-modal biological destruction by CAP treatment and their underlying mechanisms based on the latest discoveries particularly the physical effects on cancer cells.

Indexed as

cancer therapycell deathcold atmospheric plasmamicroorganism sterilizationvirus inactivation

Identifiers

PMID34572443
PMCPMC8465976

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.