Evidence map›Paper›PMID 34572423›Full record

ReviewBiomedicines2021

A Review of the Clinical and Therapeutic Implications of Neuropathic Pain.

Eleonora Balzani, Andrea Fanelli, Valentina Malafoglia, Michael Tenti, Sara Ilari, Annette Corraro, Carolina Muscoli, William Raffaeli

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Viruses · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Eleonora BalzaniDepartment of Medicine and Surgery, University of Turin, 10124 Torino, Italy.ORCID 0000-0001-7837-4457
Andrea FanelliAnesthesia, Intensive Care and Pain Therapy Unit, Department of Emergency and Urgency, Istituto ad Alta Specializzazione Policlinico di Monza, Via Amati 111, 20900 Monza, Italy.ORCID 0000-0001-9325-877X
Valentina MalafogliaISAL Foundation Institute for Research on Pain, 47922 Rimini, Italy.
Michael TentiISAL Foundation Institute for Research on Pain, 47922 Rimini, Italy.
Sara IlariDepartment of Health Science, Institute of Research for Food Safety & Health (IRC-FSH), University "Magna Graecia" of Catanzaro, Viale Europa, Loc. Germaneto, 88100 Catanzaro, Italy.
Annette CorraroFaculty of Social and Behavioural Sciences, Leiden University, 2311 Leiden, The Netherlands.
Carolina MuscoliDepartment of Health Science, Institute of Research for Food Safety & Health (IRC-FSH), University "Magna Graecia" of Catanzaro, Viale Europa, Loc. Germaneto, 88100 Catanzaro, Italy.ORCID 0000-0002-1047-4467
William RaffaeliISAL Foundation Institute for Research on Pain, 47922 Rimini, Italy.
Fondazione ISAL · ITMagna Graecia University · ITAzienda di Rilievo Nazionale ed Alta Specializzazione · ITLeiden University · NLUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding neuropathic pain presents several challenges, given the various mechanisms underlying its pathophysiological classification and the lack of suitable tools to assess its diagnosis. Furthermore, the response of this pathology to available drugs is still often unpredictable, leaving the treatment of neuropathic pain still questionable. In addition, the rise of personalized treatments further extends the ramified classification of neuropathic pain. While a few authors have focused on neuropathic pain clustering, by analyzing, for example, the presence of specific TRP channels, others have evaluated the presence of alterations in microRNAs to find tailored therapies. Thus, this review aims to synthesize the available evidence on the topic from a clinical perspective and provide a list of current demonstrations on the treatment of this disease.

Indexed as

neuropathic painpain therapytailored therapy

Identifiers

PMID34572423
PMCPMC8465811
OpenAlexW3200018714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.