Evidence map›Paper›PMID 34572334›Full record

ArticleBiomedicines2021

High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice.

Maria Kaare, Kaie Mikheim, Kersti Lilleväli, Kalle Kilk, Toomas Jagomäe, Este Leidmaa, Maria Piirsalu, Rando Porosk, Katyayani Singh, Riin Reimets and 5 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  8. Depression-AssociatedBrain sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Maria KaareInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Kaie MikheimInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.ORCID 0000-0001-6311-0993
Kersti LilleväliInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Kalle KilkCenter of Excellence in Genomics and Translational Medicine, University of Tartu, 50411 Tartu, Estonia.ORCID 0000-0003-4551-9466
Toomas JagomäeInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Este LeidmaaInstitute of Molecular Psychiatry, Medical Faculty, University of Bonn, 53129 Bonn, Germany.
Maria PiirsaluInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Rando PoroskCenter of Excellence in Genomics and Translational Medicine, University of Tartu, 50411 Tartu, Estonia.
Katyayani SinghInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Riin ReimetsInstitute of Biomedicine and Translational Medicine, Laboratory Animal Center, University of Tartu, 14B Ravila Street, 50411 Tartu, Estonia.
Egon TaalbergCenter of Excellence in Genomics and Translational Medicine, University of Tartu, 50411 Tartu, Estonia.
Michael K E SchäferDepartment of Anesthesiology, Focus Program Translational Neurosciences, Research Center for Immunotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.ORCID 0000-0001-6055-6244
Mario PlaasInstitute of Biomedicine and Translational Medicine, Laboratory Animal Center, University of Tartu, 14B Ravila Street, 50411 Tartu, Estonia.
Eero VasarInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.ORCID 0000-0001-5226-345X
Mari-Anne PhilipsInstitute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
University of Tartu · EEJohannes Gutenberg University Mainz · DEUniversity of Bonn · DE

Funding

Estonian Research Foundation PRG 685European Regional Development Fund 2014-2020.4.01.15-0012
6 · The paper itself

Abstract

In the large GWAS studies,

Indexed as

genetic modelsglucose intolerancemetabolic diseasemetabolomicsNegr1obesity

Identifiers

PMID34572334
PMCPMC8466019
OpenAlexW3197628161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.