Evidence map›Paper›PMID 34572293›Full record

ArticleBiomedicines2021

Ananta Prasad Arukha, Christian Furlan Freguia, Meerambika Mishra, Jyoti K Jha, Subhashinie Kariyawasam, Neil A Fanger, Ellen M Zimmermann, Gary R Fanger, Bikash Sahay

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Antiviral Role of Surface Layer Protein A (SlpA) ofPathogens (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ananta Prasad ArukhaDepartment of Infectious Diseases and Immunology, University of Florida, Gainesville, FL 32608, USA.
Christian Furlan FreguiaRise Therapeutics, Rockville, MD 20850, USA.
Meerambika MishraDepartment of Infectious Diseases and Immunology, University of Florida, Gainesville, FL 32608, USA.
Jyoti K JhaRise Therapeutics, Rockville, MD 20850, USA.
Subhashinie KariyawasamComparative, Diagnostic and Population Medicine, University of Florida, Gainesville, FL 32608, USA.
Neil A FangerVirtici, Seattle, WA 98122, USA.
Ellen M ZimmermannDivision of Gastroenterology, University of Florida College of Medicine, Gainesville, FL 32608, USA.
Gary R FangerRise Therapeutics, Rockville, MD 20850, USA.
Bikash SahayDepartment of Infectious Diseases and Immunology, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0003-0905-733X
University of Florida · USVirtici (United States) · US

Funding

NIDDK NIH HHS R43DK117726; R44DK117726
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation comprised of Crohn's disease and ulcerative colitis. Centers for Disease Control and Prevention report that 1.3% of the population of the United States (approximately 3 million people) were affected by the disease in 2015, and the number keeps increasing over time. IBD has a multifactorial etiology, from genetic to environmental factors. Most of the IBD treatments revolve around disease management, by reducing the inflammatory signals. We previously identified the surface layer protein A (SlpA) of

Indexed as

colitisLactococcusmicrobiome

Identifiers

PMID34572293
PMCPMC8470720
OpenAlexW3197237647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.