ReviewChildren (Basel, Switzerland)2021
NSAID Use and Effects on Pediatric Bone Healing: A Review of Current Literature.
Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Do NSAIDs affect bone healing rate, delay union, or cause non-union: an updated systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Skeletally Immature Adolescents With Open Physes Show Similar Outcomes From Hip Arthroscopy as Skeletally Mature Adolescents With Closed Physes.Arthroscopy, sports medicine, and rehabilitation · 2026Article
- Emergency Medicine Management of Distal Radius and Ulna Fractures: Narrative Review.The western journal of emergency medicine · 2026Review
- The Effect of Nonsteroidal Anti-inflammatory Drugs on Union Rates Following Joint Arthrodesis: A Meta-Analysis.Cureus · 2024Review
- Advances in Pediatric Fracture Diagnosis and Treatment Are Numerous but Great Challenges Remain.Children (Basel, Switzerland) · 2022Article
- Pediatric Fractures Are Challenging from Head to Toe.Children (Basel, Switzerland) · 2022Article
- Hepatoprotective Effect of Coenzyme Q10 in Rats with Diclofenac Toxicity.Archives of Razi Institute · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review evaluates and synthesizes the available peer-reviewed evidence regarding the impact of non-steroidal anti-inflammatory drugs (NSAIDs) on fracture healing in skeletally immature patients. Evidence supports the use of NSAIDs in this patient population for adequate pain control without increasing the risk of nonunion, particularly in long bone fractures and pseudoarthrosis after spine fusion. However, further clinical studies are needed to fill remaining gaps in knowledge, specifically with respect to the spectrum of available NSAIDs, dosage, and duration of use, in order to make broad evidence-based recommendations regarding the optimal use of NSAIDs during bone healing in skeletally immature patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.