Evidence map›Paper›PMID 34571993›Full record

ReviewCells2021

A

Stefania Gessi, Tino Emanuele Poloni, Giulia Negro, Katia Varani, Silvia Pasquini, Fabrizio Vincenzi, Pier Andrea Borea, Stefania Merighi

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Neurotransmitter Systems in Alzheimer's Disease.Current issues in molecular biology · 2026
    Review
  2. Review
  3. Review
  4. Blockade of AGeroScience · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Adenosine and adenosine receptors in metabolic imbalance-related neurological issues.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
    Review
  10. Blockade of adenosine AAlzheimer's research & therapy · 2023
    Article
  11. Review
  12. Adenosine ABiomolecules · 2023
    Article
  13. Article
  14. Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and AMolecules (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Article
  17. AInternational journal of molecular sciences · 2022
    Review
  18. Pathophysiological Role and Medicinal Chemistry of AMolecules (Basel, Switzerland) · 2022
    Review
  19. Article
  20. ACurrent medicinal chemistry · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Stefania GessiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Tino Emanuele PoloniDepartment of Neurology & Neuropathology, Golgi-Cenci Foundation, 20081 Abbiategrasso, Italy.
Giulia NegroDepartment of Neurology & Neuropathology, Golgi-Cenci Foundation, 20081 Abbiategrasso, Italy.ORCID 0000-0002-4000-786X
Katia VaraniDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-4562-1348
Silvia PasquiniDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9442-1428
Fabrizio VincenziDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-5027-1699
Pier Andrea BoreaDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Stefania MerighiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-0839-6671
University of Ferrara · ITFondazione Golgi Cenci · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is one of the most common neurodegenerative pathologies. Its incidence is in dramatic growth in Western societies and there is a need of both biomarkers to support the clinical diagnosis and drugs for the treatment of AD. The diagnostic criteria of AD are based on clinical data. However, it is necessary to develop biomarkers considering the neuropathology of AD. The A

Indexed as

AdenosineAlzheimer DiseaseBiomarkersBrainCerebral CortexEntorhinal CortexGlutamic AcidHippocampusHumansNeuronal PlasticityReceptor, Adenosine A2AReceptors, N-Methyl-D-AspartateAdenosineBiomarkersGlutamic AcidReceptor, Adenosine A2AReceptors, N-Methyl-D-Aspartateadenosine A2A receptorAlzheimer’s diseasebiomarkers

Identifiers

PMID34571993
PMCPMC8469578
OpenAlexW3198439352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.