Evidence map›Paper›PMID 34571985›Full record

ArticleCells2021

Identification of GOLPH3 Partners in

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D'Avino, Maria Grazia Giansanti

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. UsingCells · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Stefano SechiIstituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.
Angela Karimpour-GhahnaviehIstituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.
Anna FrappaoloIstituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.ORCID 0000-0002-3270-4139
Laura Di FrancescoDipartimento di Scienze Biochimiche A. Rossi Fanelli, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.
Roberto PiergentiliIstituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.ORCID 0000-0001-7584-2171
Eugenia SchininàDipartimento di Scienze Biochimiche A. Rossi Fanelli, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.
Pier Paolo D'AvinoDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.ORCID 0000-0002-4773-6950
Maria Grazia GiansantiIstituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.ORCID 0000-0002-6753-7262
Institute of Molecular Biology and Pathology · ITSapienza University of Rome · ITUniversity of Cambridge · GB

Funding

Associazione Italiana per la Ricerca sul Cancro IG2017 Id.20779Fondazione Italiana per la Ricerca sul Cancro id. 19686Royal Society International Exchanges Award 2016/R2 International Exchanges IE160510
6 · The paper itself

Abstract

Golgi phosphoprotein 3 (GOLPH3) is a highly conserved peripheral membrane protein localized to the Golgi apparatus and the cytosol. GOLPH3 binding to Golgi membranes depends on phosphatidylinositol 4-phosphate [PI(4)P] and regulates Golgi architecture and vesicle trafficking. GOLPH3 overexpression has been correlated with poor prognosis in several cancers, but the molecular mechanisms that link GOLPH3 to malignant transformation are poorly understood. We recently showed that PI(4)P-GOLPH3 couples membrane trafficking with contractile ring assembly during cytokinesis in dividing

Indexed as

AnimalsCarcinogenesisCell ProliferationCytokinesisCytoskeletonDrosophilaDrosophila ProteinsGolgi ApparatusMembrane ProteinsNervous SystemNervous System DiseasesOncogene ProteinsPhosphatidylinositol PhosphatesProtein Interaction MapsProtein TransportDrosophila ProteinsMembrane ProteinsOncogene Proteinsphosphatidylinositol 4-phosphatePhosphatidylinositol Phosphatessau protein, Drosophilacell cycleDrosophilaFMRPGolgiGOLPH3male meiosisspermatogenesis

Identifiers

PMID34571985
PMCPMC8468827
OpenAlexW3198098207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.