ArticleCells2021
Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites
Open access · goldAbstract read
In one paragraph
Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Advances in targeted liquid chromatography-tandem mass spectrometry methods for endocannabinoid and N-acylethanolamine quantification in biological matrices: A systematic review.Mass spectrometry reviewsPooled it
- Oxylipins in Atherosclerosis: Their Role in Inflammation, Diagnosis, and Therapeutic Perspectives.International journal of molecular sciences · 2025Review
- Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Non-coding RNAs at the intersection of epigenetics and cancer metabolism.Frontiers in epigenetics and epigenomics · 2025Review
- Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice.Lipids in health and disease · 2023Article
- Marine Natural and Nature-Inspired Compounds Targeting Peroxisome Proliferator Activated Receptors (PPARs).Marine drugs · 2023Review
- A Lipidomics- and Transcriptomics-Based Analysis of the Intestine of Genetically Obese (Cells · 2023Article
- Dysregulation of Bile Acids, Lipids, and Nucleotides in Psoriatic Arthritis Revealed by Unbiased Profiling of Serum Metabolites.Arthritis & rheumatology (Hoboken, N.J.) · 2023Article
- The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation.JCI insight · 2022Article
- Current knowledge of the implication of lipid mediators in psoriasis.Frontiers in immunology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 1 country.
Anne-Sophie ArchambaultCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.ORCID 0000-0001-7243-7445
Francesco TintoCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Élizabeth DumaisCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Volatiana RakotoariveloCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Magdalena KostrzewaEndocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale Delle Ricerche (CNR), 80078 Pozzuoli, Italy.
Pier-Luc PlanteInstitut sur la Nutrition et les Aliments Fonctionnels, Centre NUTRISS, École de Nutrition, Faculté des Sciences de L'agriculture et de L'alimentation, Université Laval, Québec City, QC G1V 0A6, Canada.
Cyril MartinCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Mélissa SimardCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Cristoforo SilvestriCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.ORCID 0000-0001-5635-1545
Roxane PouliotFaculté de Pharmacie de l'Université Laval and Centre de Recherche en Organogénèse Expérimentale de l'Université Laval/LOEX, Axe Médecine Régénératrice, Centre de Recherche du CHU de Québec-Université Laval, Québec City, QC G1V 0A6, Canada.ORCID 0000-0002-2423-9599
Michel LavioletteCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Louis-Philippe BouletCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Rosa Maria VitaleEndocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale Delle Ricerche (CNR), 80078 Pozzuoli, Italy.ORCID 0000-0001-9243-1307
Alessia LigrestiEndocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale Delle Ricerche (CNR), 80078 Pozzuoli, Italy.ORCID 0000-0003-1787-3900
Vincenzo Di MarzoCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.
Nicolas FlamandCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculté de Médecine, Université Laval, Québec City, QC G1V 4G5, Canada.ORCID 0000-0001-5944-7200
Institut universitaire de cardiologie et de pneumologie de Québec · CAUniversité Laval · CA
Funding
CIHRNational Sciences and Engineering Research Council of Canada RGPIN-2015-04728National Sciences and Engineering Research Council of Canada RGPIN-2021-03777
Abstract
The endocannabinoids 2-arachidonoyl-glycerol and
Indexed as
AnimalsArachidonate 15-LipoxygenaseEosinophilsHumansKineticsLinoleic AcidsMiceMolecular Docking SimulationNeutrophilsPeroxisome Proliferator-Activated ReceptorsProtein BindingReceptors, CannabinoidSubstrate SpecificityTRPV Cation ChannelsArachidonate 15-LipoxygenaseLinoleic AcidsPeroxisome Proliferator-Activated ReceptorsReceptors, CannabinoidTRPV1 protein, humanTRPV Cation Channels13-HODE2-arachidonoyl-glycerolanandamideeicosanoidendocannabinoideosinophilslinoleic acidlinoleoyl-glycerolneutrophilsN-linoleoyl-ethanolamine
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.