Evidence map›Paper›PMID 34571959›Full record

ArticleCells2021

Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.

Marina Di Domenico, Melanie Jokwitz, Walter Witke, Pietro Pilo Boyl

Abstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marina Di DomenicoInstitute of Genetics, University of Bonn, 53115 Bonn, Germany.
Melanie JokwitzInstitute of Genetics, University of Bonn, 53115 Bonn, Germany.
Walter WitkeInstitute of Genetics, University of Bonn, 53115 Bonn, Germany.
Pietro Pilo BoylInstitute of Genetics, University of Bonn, 53115 Bonn, Germany.ORCID 0000-0002-7535-4802

Funding

Deutsche Forschungsgemeinschaft SFB1089Deutsche Forschungsgemeinschaft SPP1464
6 · The paper itself

Abstract

Profilin functions have been discussed in numerous cellular processes, including actin polymerization. One puzzling aspect is the concomitant expression of more than one profilin isoform in most tissues. In neuronal precursors and in neurons,

Indexed as

AnimalsBrainCell DifferentiationMiceNeuronsProfilinsProtein IsoformsPfn1 protein, mousePfn2 protein, mouseProfilinsProtein Isoformsactinbrain developmentcell divisionneuronal branchingneuronal precursor cellsprofilin

Identifiers

PMID34571959
PMCPMC8467068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.