Evidence map›Paper›PMID 34571913›Full record

ArticleCells2021

Jian Lin, Lulu Huang, Yuchen Li, Penghao Zhang, Qinghua Yu, Qian Yang

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Disruption of Spore Coat Integrity inCurrent issues in molecular biology · 2025
    Article
  3. Trained Innate Immunity in Animal Models of Cardiovascular Diseases.International journal of molecular sciences · 2024
    Review
  4. Immune Responses Induced by RecombinantVeterinary sciences · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jian LinCollege of Life Sciences, Nanjing Agricultural University, Weigang 1, Nanjing 210095, China.ORCID 0000-0003-0455-9736
Lulu HuangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing 210095, China.
Yuchen LiMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing 210095, China.
Penghao ZhangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing 210095, China.
Qinghua YuMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing 210095, China.
Qian YangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing 210095, China.ORCID 0000-0002-2349-0028
Nanjing Agricultural University · CN

Funding

Jiangsu Excellent Youth Natural Science Foundation (BK20190077)National Natural Science Foundation of China (32072835, 31702197
6 · The paper itself

Abstract

Immunological memory is a cardinal feature of the immune system. The intestinal mucosa is the primary exposure and entry site of infectious organisms. For an effective and long-lasting safeguard, a robust immune memory system is required, especially by the mucosal immunity. It is well known that tissue-resident memory T cells (Trms) provide a first response against infections reencountered at mucosal tissues surfaces, where they accelerate pathogen clearance. However, their function in intestinal immunization remains to be investigated. Here, we report enhanced local mucosal and systemic immune responses through oral administration of H9N2 influenza whole inactivated virus (H9N2 WIV) plus

Indexed as

Adjuvants, ImmunologicAnimalsAntibodies, ViralBacillus subtilisDendritic CellsImmunizationImmunologic MemoryInfluenza A Virus, H9N2 SubtypeIntercellular Adhesion Molecule-1Intestinal MucosaMiceMice, Inbred BALB CMice, Inbred C57BLSpores, BacterialT-LymphocytesAdjuvants, ImmunologicAntibodies, ViralIntercellular Adhesion Molecule-1Acrp30Bacillus subtilis sporedendritic cellICAM1intestinal-resident memory T cells

Identifiers

PMID34571913
PMCPMC8469252
OpenAlexW3197777786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.