Evidence map›Paper›PMID 34571901›Full record

ArticleCells2021

Housekeeping Genes for Parkinson's Disease in Humans and Mice.

Anelya Kh Alieva, Elena V Filatova, Margarita M Rudenok, Petr A Slominsky, Maria I Shadrina

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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  8. Analysis ofBiomedicines · 2024
    Article
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  11. Analysis ofBioMed research international · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anelya Kh AlievaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.ORCID 0000-0002-6200-4491
Elena V FilatovaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.ORCID 0000-0002-8704-7455
Margarita M RudenokInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.ORCID 0000-0002-6524-9101
Petr A SlominskyInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.
Maria I ShadrinaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.
Kurchatov Institute · RU

Funding

Russian Science Foundation 20-15-00262
6 · The paper itself

Abstract

A critical aspect of real-time PCR is the presence of housekeeping genes (HKGs) as an internal control for the normalization of expression data for genes of interest. It is necessary to select correct HKGs in the investigation of various pathologies. Thereby, we analyzed the stability of expression of the HKGs in Parkinson's disease (PD). The work was carried out in the peripheral blood of patients with PD and in the brain tissues and peripheral blood of mice with MPTP-induced PD. As a result,

Indexed as

Gene Expression RegulationGenes, EssentialAgedAnimalsCase-Control StudiesFemaleGene Expression ProfilingHumansMaleMiceMice, Inbred C57BLMiddle AgedParkinson DiseaseReference StandardsRNA, MessengerRNA, Messengergene expressionhousekeeping geneneurodegenerationParkinson’s diseasereal-time PCRreference geneTaqMan

Identifiers

PMID34571901
PMCPMC8470043
OpenAlexW3196997999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.