Evidence map›Paper›PMID 34571882›Full record

ArticleCells2021

Hypoblast Formation in Bovine Embryos Does Not Depend on NANOG.

Claudia Springer, Valeri Zakhartchenko, Eckhard Wolf, Kilian Simmet

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Pluripotent Core in Bovine Embryos: A Review.Animals : an open access journal from MDPI · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Claudia SpringerInstitute of Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, Ludwig-Maximilians-Universität München, 85764 Oberschleissheim, Germany.ORCID 0000-0002-1155-3570
Valeri ZakhartchenkoInstitute of Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, Ludwig-Maximilians-Universität München, 85764 Oberschleissheim, Germany.ORCID 0000-0002-5974-9759
Eckhard WolfInstitute of Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, Ludwig-Maximilians-Universität München, 85764 Oberschleissheim, Germany.ORCID 0000-0002-0430-9510
Kilian SimmetInstitute of Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, Ludwig-Maximilians-Universität München, 85764 Oberschleissheim, Germany.ORCID 0000-0003-2188-3108
Ludwig-Maximilians-Universität München · DE

Funding

Bayerische Forschungsstiftung AZ-1300-17Deutsche Forschungsgemeinschaft 405453332German Center for Diabetes Research 82DZD00802.
6 · The paper itself

Abstract

The role of the pluripotency factor NANOG during the second embryonic lineage differentiation has been studied extensively in mouse, although species-specific differences exist. To elucidate the role of NANOG in an alternative model organism, we knocked out

Indexed as

AnimalsApoptosisBlastocystCattleCell DifferentiationCell LineageCRISPR-Cas SystemsEmbryo, MammalianGene EditingGerm LayersMiceMice, KnockoutMitogen-Activated Protein Kinase KinasesNanog Homeobox ProteinProtein Kinase InhibitorsSignal TransductionMitogen-Activated Protein Kinase KinasesNanog Homeobox ProteinProtein Kinase InhibitorsSOXF Transcription Factorsbovine preimplantation developmentMEKNANOGsecond lineage differentiationSOX17

Identifiers

PMID34571882
PMCPMC8466907
OpenAlexW3196835192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.