Evidence map›Paper›PMID 34571843›Full record

ArticleCells2021

Gut Leakage Markers in Response to Strenuous Exercise in Patients with Suspected Coronary Artery Disease.

Susanne Kristine Aune, Joanna Cwikiel, Arnljot Flaa, Harald Arnesen, Svein Solheim, Ayodeji Awoyemi, Marius Trøseid, Ingebjørg Seljeflot, Ragnhild Helseth

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Susanne Kristine AuneCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Joanna CwikielCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Arnljot FlaaDepartment of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Harald ArnesenCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Svein SolheimCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Ayodeji AwoyemiCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Marius TrøseidFaculty of Medicine, University of Oslo, 0316 Oslo, Norway.ORCID 0000-0001-7775-3404
Ingebjørg SeljeflotCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.ORCID 0000-0003-4071-3358
Ragnhild HelsethCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, 0424 Oslo, Norway.
Oslo University Hospital · NO

Funding

Stein Erik Hagen Foundation for Clinical Heart Research Has no numberUniversity of Oslo Has no number
6 · The paper itself

Abstract

Elevated levels of gut leakage markers have been shown after strenuous exercise in healthy individuals. Any association between a temporary increase in these markers and the presence of coronary artery disease (CAD) is unknown. We therefore aimed to explore circulating gut leakage markers in response to a bout of strenuous exercise in patients with symptoms of CAD. Patients referred to exercise stress testing due to symptoms of CAD were included (

Indexed as

Acute-Phase ProteinsAdultAgedAged, 80 and overBiomarkersCarrier ProteinsCoronary AngiographyCoronary Artery DiseaseDigestive SystemExerciseExercise TestFemaleHumansLipopolysaccharide-Binding ProteinMaleMembrane GlycoproteinsAcute-Phase ProteinsBiomarkersCarrier ProteinsLipopolysaccharide-Binding ProteinMembrane GlycoproteinsToll-Like Receptor 4acute exercisecardiovascular diseasegut leakageinflammationmicrobiotastrenuous exercise

Identifiers

PMID34571843
PMCPMC8466709
OpenAlexW3195673594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.