ArticleBiology2021
Clinical Relevance of the Microbiome in Odontogenic Abscesses.
Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Treatment of Odontogenic Sinusitis With Oroantral Communication and Fistula:Saudi medical journal · 2026Pooled it
- Brucella abortus-induced neck abscess: a case report in an urban area of Miranda, Venezuela.BMC infectious diseases · 2026Article
- Quantitative PCR-Based Analysis of Bacterial Profiles in Periapical Lesions and Maxillary Sinus in Odontogenic Sinusitis.International journal of molecular sciences · 2026Article
- Dynamics of Inflammatory Parameters in Hospitalized and Surgically Treated Patients with Odontogenic Abscesses.Medicina (Kaunas, Lithuania) · 2026Article
- Paired oral clinical specimens reveal the underlying ecology supporting the emergence of inflammophilic microbiome communities.bioRxiv : the preprint server for biology · 2026Article
- The critical role of 16S rRNA sequencing in diagnosis and management of an odontogenic deep neck abscess: A case report.IDCases · 2026Article
- Injectable Fillers for Atrophic Acne Scars: A Systematic Review of Mechanisms, Evidence, and Clinical Algorithms.Clinical, cosmetic and investigational dermatology · 2026Review
- Microbiological and Clinical Predictors of Surgical Intervention in Odontogenic Sinusitis.Journal of clinical medicine · 2025Article
- Next-generation sequencing improves pathogen identification in odontogenic abscesses, could this affect clinical outcomes?Clinical oral investigations · 2025Review
- PediatricJournal of fungi (Basel, Switzerland) · 2025Article
- Epidemiological characteristics and risk factors for prolonged hospitalisation in oral and maxillofacial space infections: a 3-year retrospective study of 217 cases.BMC oral health · 2025Article
- Odontogenic Cutaneous Fistula in Pregnant Woman: Is Long-Term Antibiotic Therapy the Solution?Cureus · 2025Article
- Microbial spectrum and resistance of odontogenic abscesses - microbiological analysis using next generation sequencing.Clinical oral investigations · 2024Article
- Use of pus metagenomic next-generation sequencing for efficient identification of pathogens in patients with sepsis.Folia microbiologica · 2024Article
- Forecasting the development of antimicrobial resistance ofFrontiers in oral health · 2024Article
- Outcome predictors of odontogenic abscesses in the elderly.Frontiers in oral health · 2024Article
- Metagenomic next-generation sequencing for the diagnosis of oral and maxillofacial space infections.Journal of dental sciences · 2023Article
- Sonication versus the conventional method for evaluation of the dental microbiome: a prospective pilot study.BMC oral health · 2022Article
- Odontogenic Cervicofacial Necrotizing Fasciitis: Microbiological Characterization and Management of Four Clinical Cases.Pathogens (Basel, Switzerland) · 2022Article
- Review
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
Odontogenic abscesses are usually caused by bacteria of the oral microbiome. However, the diagnostic culture of these bacteria is often prone to errors and sometimes fails completely due to the fastidiousness of the relevant bacterial species. The question arises whether additional pathogen diagnostics using molecular methods provide additional benefits for diagnostics and therapy. Experimental 16S rRNA gene analysis with next-generation sequencing (NGS) and bioinformatics was used to identify the microbiome of the pus in patients with severe odontogenic infections and was compared to the result of standard diagnostic culture. The pus microbiome was determined in 48 hospitalized patients with a severe odontogenic abscess in addition to standard cultural pathogen detection. Cultural detection was possible in 41 (85.42%) of 48 patients, while a pus-microbiome could be determined in all cases. The microbiomes showed polymicrobial infections in 46 (95.83%) cases, while the picture of a mono-infection occurred only twice (4.17%). In most cases, a predominantly anaerobic spectrum with an abundance of bacteria was found in the pus-microbiome, while culture detected mainly
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.