Evidence map›Paper›PMID 34571791›Full record

ArticleBiology2021

Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors.

Carolin Hessinger, Martin Schüßler, Sabrina Klos, Markus Kochanek, Rolf Jakoby

Open access · goldAbstract read
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Image-based computer modeling assessment of microwave ablation for treatment of adrenal tumors.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Carolin HessingerInstitute for Microwave Engineering and Photonics, Technische Universität Darmstadt, Merckstr. 25, 64283 Darmstadt, Germany.
Martin SchüßlerInstitute for Microwave Engineering and Photonics, Technische Universität Darmstadt, Merckstr. 25, 64283 Darmstadt, Germany.
Sabrina KlosCommunications Engineering Lab, Technische Universität Darmstadt, 64289 Darmstadt, Germany.
Markus KochanekInstitute for Microwave Engineering and Photonics, Technische Universität Darmstadt, Merckstr. 25, 64283 Darmstadt, Germany.
Rolf JakobyInstitute for Microwave Engineering and Photonics, Technische Universität Darmstadt, Merckstr. 25, 64283 Darmstadt, Germany.
Merck (Germany) · DETechnical University of Darmstadt · DE

Funding

Deutsche Forschungsgemeinschaft JA-921/52-2
6 · The paper itself

Abstract

A multiobjective optimization method for a dual-mode microwave applicator is proposed. Dual-modality means that microwaves are used apart from the treatment, and also for the monitoring of the microwave ablation intervention. (1) The use of computational models to develop and improve microwave ablation applicator geometries is essential for further advances in this field. (2) Numerical electromagnetic-thermal coupled simulation models are used to analyze the performance of the dual-mode applicator in liver tissue; the sensitivity evaluation of the dual-mode applicator's sensing mode constrains the set of optimal solutions. (3) Three Pareto-optimal design parameter sets are derived that are optimal in terms of applicator efficiency as well as volume and sphericity of the ablation zone. The resulting designs of the dual-mode applicator provide a suitable sensitivity to distinguish between healthy and tumorous liver tissue. (4) The optimized designs are presented and numerically characterized. An improvement on the performance of previously proposed dual-mode applicator designs is achieved. The multiphysical simulation model of electromagnetic and thermal properties of the applicator is applicable for future comprehensive design procedures.

Indexed as

microwave ablationmicrowave applicatormultiobjective optimization

Identifiers

PMID34571791
PMCPMC8467388
OpenAlexW3201609742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.