Evidence map›Paper›PMID 34571639›Full record

ArticleIndian journal of ophthalmology2021

COVID-19 positivity rate in corneal tissue donors - A cause for concern!

Sharon D'Souza, Rohit Shetty, Gairik Kundu, Namrata Sharma, Radhika Tandon, Himanshu Matalia, Bhavya Gorimanipalli, Chaitra Jayadev

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Immediate impact of COVID-19 on eye banking in India.Indian journal of ophthalmology · 2021
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sharon D'SouzaDepartment of Cornea and Refractive Services, Narayana Nethralaya, Bangalore, Karnataka, India.
Rohit ShettyDepartment of Cornea and Refractive Services, Narayana Nethralaya, Bangalore, Karnataka, India.
Gairik KunduDepartment of Cornea and Refractive Services, Narayana Nethralaya, Bangalore, Karnataka, India.
Namrata SharmaCornea, Cataract and Refractive Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Radhika TandonCornea, Cataract and Refractive Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Himanshu MataliaDepartment of Cornea and Refractive Services, Narayana Nethralaya, Bangalore, Karnataka, India.
Bhavya GorimanipalliDepartment of Cornea and Refractive Services, Narayana Nethralaya, Bangalore, Karnataka, India.
Chaitra JayadevDepartment of Vitreoretina Services, Narayana Nethralaya, Bangalore, Karnataka, India.
Narayana Nethralaya · INAll India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To determine the postmortem positivity for COVID-19 among voluntary eye donors who had been certified to have died of non-COVID-19 causes. Methods: All donors who donated their corneas (from March 2021 onward) were assessed for COVID-19 positivity tested by nasopharyngeal swab reverse transcription-polymerase chain reaction (RT-PCR) test. Relevant screening history was taken prior to collection. Strict precautions were taken during the retrieval as per the guidelines issued by the National Program for Control of Blindness and Visual Impairment and the Eye Bank Association of India, and the tissues were handled as per standard operating protocol. Results: 85 eye calls were attended during this period, of which 56 were home-based and 29 were from a hospital setting. Samples from 12 of the former group of donors were found to be positive for COVID-19 (14%). Conclusion: This study highlights the possibility of postmortem RT-PCR positivity in voluntary corneal tissue donors without a prior history of symptoms, signs, or diagnosis of illness suggestive of COVID-19. It is recommended that postmortem testing of donors should be done by RT-PCR for retrievals made during the pandemic.

Indexed as

COVID-19CorneaEye BanksHumansSARS-CoV-2Tissue DonorsCOVID-19donor corneaseye bankingriskstandard operating protocol

Identifiers

PMID34571639
PMCPMC8597523
OpenAlexW3203705499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.