Evidence map›Paper›PMID 34571623›Full record

ArticleIndian journal of ophthalmology2021

Clinical profile and outcomes of neovascular glaucoma in the era of anti-vascular endothelial growth factor.

Vishwesh Sirish Malgi, Lisika Gawas, Archana Suresh Iyer, Aparna Rao

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Clinical outcomes of the PAUL Glaucoma implant for neovascular glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Vishwesh Sirish MalgiGlaucoma Services, LV Prasad Eye Institute, Patia, Bhubaneswar, Odisha, India.
Lisika GawasGlaucoma Services, LV Prasad Eye Institute, Patia, Bhubaneswar, Odisha, India.
Archana Suresh IyerGlaucoma Services, LV Prasad Eye Institute, Patia, Bhubaneswar, Odisha, India.
Aparna RaoGlaucoma Services, LV Prasad Eye Institute, Patia, Bhubaneswar, Odisha, India.
Christie's · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the clinical profile and visual impairment in various stages of neovascular glaucoma (NVG) at a tertiary eye center in East India.

methodsThe electronic medical records of the hospital database of patients with neovascular glaucoma seen between 2013 and 2020 were reviewed. Gonioscopic details were used to stratify patients into nonspecified NVG (Group 1), open-angle NVG (Group 2), and closed-angle NVG (Group 3). The clinical profile, angle features, cause of NVG, systemic associations, visual impairment, and blindness (defined as logarithm of the minimum angle of resolution, LogMar >1.3 at baseline and at final follow-up), and outcomes of medical/surgical interventions were compared between the three groups.

resultsOf 846 eyes of 810 patients with NVG (Group 1, n = 564 eyes, Group 2, n = 61 eyes, and Group 3, n = 220 eyes), at baseline, the blindness rates in Groups 3 and 2 were 90 and 75%, respectively. The time from a previous intervention to the onset of NVG ranged from 3 to 5 months, while the median duration of NVG was about 4-4.5 months (0.03-120 months). Multivariate regression identified a longer duration of NVG as the only variable associated with poor final visual acuity.

conclusionVisual morbidity by NVG remains as high as 75-90% in developing countries, even with the availability of anti-VEGFs and after improved management/investigative at all stages.

Indexed as

Glaucoma, NeovascularBevacizumabEyeHumansIntraocular PressureVascular Endothelial Growth Factor ABevacizumabVascular Endothelial Growth Factor AAnti-VEGFblindnessneovascular glaucomarubeotic glaucomasecondary glaucoma

Identifiers

PMID34571623
PMCPMC8597518
OpenAlexW3203057625

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.