Evidence map›Paper›PMID 34570951›Full record

ArticleImmunity, inflammation and disease2022

Characterising the allergic profile of children with cystic fibrosis.

Amy L Faulkner, Michael Grayling, Benjamin Shillitoe, Malcolm Brodlie, Louise J Michaelis

Open access · goldAbstract read
In one paragraph

Article in Immunity, inflammation and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amy L FaulknerFaculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0001-5390-3869
Michael GraylingPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-0680-6668
Benjamin ShillitoeDepartment of Immunology, Allergy, and Infectious Diseases, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.ORCID 0000-0003-4407-5998
Malcolm BrodlieTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-4591-8299
Louise J MichaelisPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0001-8229-154X
Newcastle upon Tyne Hospitals NHS Foundation Trust · GBNewcastle University · GB

Funding

Medical Research Council MR/M008797/1
6 · The paper itself

Abstract

backgroundCystic fibrosis (CF) is a genetic condition that affects multiple organ systems. Allergic bronchopulmonary aspergillosis (ABPA) is a well-recognised problem but other allergic conditions are less well documented in CF.

objectiveTo characterise the allergic profile of a cohort of children with CF, with a focus on those with ABPA.

methodsA cohort of children with CF were interviewed and retrospective data were collected regarding their allergic histories and other relevant clinical features.

resultsThe cohort included 37 children with median age of 9 years (interquartile range: 6-12). There was a history of ≥1 allergic condition(s) in 28/37 children (76%). The most common allergic condition was allergic rhinitis (AR) in 21/37 (57%) and 16 of these 21 children (76%) had another allergic condition. All children with ABPA (8) had another allergic condition. In some children ABPA exacerbations appeared to be seasonal, suggesting possible cross-sensitisation between Aspergillus fumigatus and aeroallergens associated with seasonal AR. Allergic conditions were also common in children with Pseudomonas aeruginosa infection.

Indexed as

Aspergillosis, Allergic BronchopulmonaryCystic FibrosisAllergensAspergillus fumigatusChildHumansRetrospective StudiesAllergensallergic rhinitisAspergilluscystic fibrosishypersensitivity

Identifiers

PMID34570951
PMCPMC8669696
OpenAlexW3203805356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.