ArticleScandinavian journal of work, environment & health2022
Cancer-related changes and low-to-moderate exposure to welding fumes: A longitudinal study.
Article in Scandinavian journal of work, environment & health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Metals (Cr, Mn, Co, Ni) concentration in the blood plasma and urine od Polish welders and telomere length as an potential indicator of toxicity of metals welding fumes exposure.International journal of occupational medicine and environmental health · 2025Article
- Five decades of occupational cancer epidemiology.Scandinavian journal of work, environment & health · 2024Review
- Longitudinal changes in cardiovascular disease-related proteins in welders.International archives of occupational and environmental health · 2024Article
- Toxicomethylomics revisited: A state-of-the-science review about DNA methylation modifications in blood cells from workers exposed to toxic agents.Frontiers in public health · 2023Review
- Metal Exposure-Related Welder's Pneumoconiosis and Lung Function: A Cross-Sectional Study in a Container Factory of China.International journal of environmental research and public health · 2022Article
- Toxicity of stainless and mild steel particles generated from gas-metal arc welding in primary human small airway epithelial cells.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study tested for an association between early cancer-related biomarkers and low-to-moderate exposure to fumes from welding mild steel.
methodsMale, non-smoking participants from southern Sweden were recruited and examined (N=338, 171 welders and 167 controls); of these, 78 welders and 96 controls were examined on two occasions six years apart. Exposure to welding fumes was evaluated by measuring respirable dust, welding years, and cumulative exposure. DNA methylation of CpG sites within the cancer-related genes AHRR, F2RL3, and B3GNTL1 was measured by pyrosequencing and relative mitochondrial DNA copy number and telomere length were measured by qPCR in whole-blood samples. Multivariate models were used for longitudinal analysis.
resultsMedian exposure to respirable dust was 0.7 mg/m
conclusionLow-to-moderate exposure to welding fumes was associated with a small effect on selected early epigenetic biomarkers of cancer. The direction of the methylation pattern (lower methylation of specific CpG sites) indicates early lung cancer-related changes associated with mild steel welding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.