ArticleeLife2021
Hippocampal replay of experience at real-world speeds.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- Integrating neural decoding, memristive materials, and adaptive control frameworks for next-generation hippocampal memory prosthetics.iScience · 2026Review
- Replay of procedural memory is independent of the hippocampus.Nature neuroscience · 2026Article
- Drift-diffusion dynamics of hippocampal replay.PLoS computational biology · 2026Article
- Article
- The hippocampus as a small-world cognitive map.bioRxiv : the preprint server for biology · 2026Article
- Naturalistic behavior and self-generated neural activity predictive of self-correction.bioRxiv : the preprint server for biology · 2026Article
- Entorhinal cortex represents task-relevant remote locations independently of CA1.Nature neuroscience · 2026Article
- Sharp wave-ripple clusters enhance hippocampal-neocortical engagement for memory consolidation.bioRxiv : the preprint server for biology · 2026Article
- Dynamical modulation of hippocampal replay through firing rate adaptation.Nature communications · 2026Article
- Article
- Subspace communication in the hippocampal-retrosplenial axis.bioRxiv : the preprint server for biology · 2026Article
- A State-Space Framework for Causal Detection of Hippocampal Ripple-Replay Events.IEEE transactions on bio-medical engineering · 2026Article
- Article
- Replay without sharp wave ripples in a spatial memory task.Nature communications · 2025Article
- Pre-existing and emergent cortical neuronal assembly sequences during learning.bioRxiv : the preprint server for biology · 2025Article
- Ripple contributions to human memory: making the spiking content count.Nature reviews. Neuroscience · 2025Review
- Disruption of theta-timescale spiking impairs learning but spares hippocampal replay.bioRxiv : the preprint server for biology · 2025Article
- Reading specific memories from human neurons before and after sleep.bioRxiv : the preprint server for biology · 2025Article
- Altered patterning of neural activity in a neuropathology.Scientific reports · 2025Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Representations related to past experiences play a critical role in memory and decision-making processes. The rat hippocampus expresses these types of representations during sharp-wave ripple (SWR) events, and previous work identified a minority of SWRs that contain 'replay' of spatial trajectories at ∼20x the movement speed of the animal. Efforts to understand replay typically make multiple assumptions about which events to examine and what sorts of representations constitute replay. We therefore lack a clear understanding of both the prevalence and the range of representational dynamics associated with replay. Here, we develop a state space model that uses a combination of movement dynamics of different speeds to capture the spatial content and time evolution of replay during SWRs. Using this model, we find that the large majority of replay events contain spatially coherent, interpretable content. Furthermore, many events progress at real-world, rather than accelerated, movement speeds, consistent with actual experiences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.