Evidence map›Paper›PMID 34570693›Full record

ArticleEmerging infectious diseases2021

Human Melioidosis Caused by Novel Transmission of Burkholderia pseudomallei from Freshwater Home Aquarium, United States

Patrick Dawson, Monique M Duwell, Mindy G Elrod, Ruth J Thompson, David A Crum, Ruth M Jacobs, Jay E Gee, Cari B Kolton, Lindy Liu, David D Blaney and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Melioidosis Complicated by Native Valve Endocarditis in a Traveler Returning From Thailand to the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Infection and drug resistance · 2025
    Review
  8. Case Report: Genetic evolution ofWellcome open research · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. mSphere · 2023
    Article
  16. The Expanding Global Footprint of Burkholderia pseudomallei and Melioidosis.The American journal of tropical medicine and hygiene · 2023
    Article
  17. Article
  18. Article
  19. Melioidosis in Cynomolgus Macaques (Comparative medicine · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Patrick Dawson
Monique M Duwell
Mindy G Elrod
Ruth J Thompson
David A Crum
Ruth M Jacobs
Jay E Gee
Cari B Kolton
Lindy Liu
David D Blaney
LaToya Griffin Thomas
Denise Sockwell
Zachary Weiner
William A Bower
Alex R Hoffmaster
Johanna S Salzer
Department of General Services · USCenters for Disease Control and Prevention · USMaryland Department of Health · USCollege of the Holy Cross · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nearly all cases of melioidosis in the continental United States are related to international travel to areas to which Burkholderia pseudomallei, the bacterium that causes melioidosis, is endemic. We report the diagnosis and clinical course of melioidosis in a patient from the United States who had no international travel history and the public health investigation to determine the source of exposure. We tested environmental samples collected from the patient's home for B. pseudomallei by PCR and culture. Whole-genome sequencing was conducted on PCR-positive environmental samples, and results were compared with sequences from the patient's clinical specimen. Three PCR-positive environmental samples, all collected from a freshwater home aquarium that had contained imported tropical fish, were a genetic match to the clinical isolate from the patient. This finding suggests a novel route of exposure and a potential for importation of B. pseudomallei, a select agent, into the United States from disease-endemic areas.

Indexed as

Burkholderia pseudomalleiMelioidosisAnimalsFresh WaterHumansPolymerase Chain ReactionUnited StatesWhole Genome SequencingbacteriaBurkholderia pseudomalleifreshwater home aquariumhuman infectionimported tropical fishMarylandmelioidosisOne HealthpetsSoutheast AsiatransmissionUnited Stateswhole-genome sequencingzoonoses

Identifiers

PMID34570693
PMCPMC8632198
OpenAlexW3203483701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.