Evidence map›Paper›PMID 34570646›Full record

ArticleAntimicrobial agents and chemotherapy2021

Uropathogenic Escherichia coli Shows Antibiotic Tolerance and Growth Heterogeneity in an

Ivana Kerkez, Paul M Tulkens, Tanel Tenson, Françoise Van Bambeke, Marta Putrinš

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Intracellular persister: A stealth agent recalcitrant to antibiotics.Frontiers in cellular and infection microbiology · 2023
    Review
  6. Article
  7. Antibiotic persistence of intracellular Brucella abortus.PLoS neglected tropical diseases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ivana KerkezPharmacologie cellulaire et moléculaire, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Paul M TulkensPharmacologie cellulaire et moléculaire, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Tanel TensonInstitute of Technology, University of Tartugrid.10939.32, Tartu, Estonia.
Françoise Van Bambeke *Pharmacologie cellulaire et moléculaire, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.ORCID 0000-0002-0052-7991
Marta Putrinš *Institute of Technology, University of Tartugrid.10939.32, Tartu, Estonia.ORCID 0000-0003-1492-2826

Funding

EC | European Regional Development Fund (ERDF) 2014-2020.4.01.15-0013Fonds De La Recherche Scientifique - FNRS (FNRS) T.0189.16Ministry of Education and Research | Estonian Research Competency Council (Research Competency Council) PRG335Sihtasutus Archimedes (Archimedes Foundation) Dora Plus scholarship
6 · The paper itself

Abstract

Uropathogenic Escherichia coli (UPEC), the major causative agent of urinary tract infections, can invade different types of host cells. To compare the pharmacodynamic properties of antibiotics against intra- and extracellular UPEC, an

Indexed as

Escherichia coli InfectionsUrinary Tract InfectionsUropathogenic Escherichia coliAnimalsAnti-Bacterial AgentsCiprofloxacinMiceAnti-Bacterial AgentsCiprofloxacinflow cytometryfluorescent reporterfluoroquinolonesintracellular infectionmacrophagespersisterspharmacodynamicsTIMERbacUPECUTI

Identifiers

PMID34570646
PMCPMC8597737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.