Evidence map›Paper›PMID 34570408›Full record

ArticleThe American journal on addictions2022

Motives for prescription opioid use: The role of alexithymia and distress tolerance.

Aisling V Henschel, Julianne C Flanagan, Isabel F Augur, Stephanie M Jeffirs, Sudie E Back

Abstract read
In one paragraph

Article in The American journal on addictions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aisling V HenschelDepartment of Psychology, University of Missouri-Kansas City, Kansas City, Missouri, USA.ORCID 0000-0003-3107-8428
Julianne C FlanaganDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0002-4277-232X
Isabel F AugurDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.
Stephanie M JeffirsDepartment of Psychological Sciences, Auburn University, Auburn, Alabama, USA.
Sudie E BackDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.

Funding

TRANSLATIONAL RESEARCH TRAINING: STRESS AND ADDICTIONK23DA021228 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2007 to 2011
$842k
Integrating Neurobiology and Neuroimaging into Research on Addiction and PTSDK02DA039229 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2015 to 2019
$779k
Effects of Oxytocin on Alcohol Craving and Intimate Partner AggressionK23AA023845 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FLANAGAN, JULIANNE CHRISTINA · 2016 to 2019
$774k
NIAAA NIH HHS K23 AA023845NIAAA NIH HHS K23AA02385NIDA NIH HHS K02 DA039229NIDA NIH HHS K23 DA021228
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPrescription opioid (PO) use disorder is a national public health crisis. Distress tolerance and alexithymia are two separate but related components of emotion regulation that are known to impact substance use disorders. No studies to date, however, have examined the role of distress tolerance and alexithymia in PO use disorder. Thus, the current study examined the association between distress tolerance, alexithymia, and specific motivations for PO use.

methodsParticipants were non-treatment-seeking individuals with current PO use disorder (N = 81; average age = 35.0). Assessments included the Distress Tolerance Scale, Toronto Alexithymia Scale, and the Inventory of Drug Taking Situations.

resultsThe findings indicate that distress tolerance mediated the association between alexithymia and PO use in negative situations. Specifically, distress tolerance mediated the association between alexithymia and unpleasant emotions, testing personal control, and conflict with others. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: The results provide novel information regarding emotional states that may contribute to PO use and are malleable intervention targets. Additionally, this study adds to existing literature exploring the relationship between distress tolerance and substance use and is the first to expand upon the connection between alexithymia and distress tolerance in an opioid-using population. Implications for clinical practice and future research are discussed.

Indexed as

Analgesics, OpioidOpioid-Related DisordersAdultAffective SymptomsEmotionsHumansMotivationPrescriptionsAnalgesics, Opioid

Identifiers

PMID34570408
PMCPMC8799478

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.