Evidence map›Paper›PMID 34570405›Full record

Trial reportJournal of intellectual disability research : JIDR2021

A pilot randomised controlled trial of befriending by volunteers in people with intellectual disability and depressive symptoms.

A Ali, E McKenzie, A Hassiotis, S Priebe, B Lloyd-Evans, R Jones, M Panca, R Omar, S Finning, S Moore and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of intellectual disability research : JIDR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Systematic Review of Loneliness and Social Isolation Interventions in Obesity and Obesity-Related Complications.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Pooled it
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  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Social Inclusion of Adults with Intellectual and Developmental Disabilities: Toward Belonging.International review of research in developmental disabilities · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

A AliEpidemiology and Applied Clinical Research Department, Division of Psychiatry, University College London, London, UK.ORCID 0000-0002-0104-9370
E McKenzieResearch and Development Office, Goodmayes Hospital, North East London NHS Foundation Trust, London, UK.
A HassiotisEpidemiology and Applied Clinical Research Department, Division of Psychiatry, University College London, London, UK.
S PriebeUnit for Social and Community Psychiatry, WHO Collaborating Centre for Mental Health Services Development, Queen Mary University of London, London, UK.
B Lloyd-EvansEpidemiology and Applied Clinical Research Department, Division of Psychiatry, University College London, London, UK.
R JonesEpidemiology and Applied Clinical Research Department, Division of Psychiatry, University College London, London, UK.
M PancaPriment Clinical Trials Unit, University College London, London, UK.
R OmarDepartment of Statistical Science, University College London, London, UK.
S FinningOutward Housing, Outward, Newlon House, London, UK.
S MooreThe Befriending Scheme, Sudbury, Suffolk, UK.
C RoeThe Befriending Scheme, Sudbury, Suffolk, UK.
M KingEpidemiology and Applied Clinical Research Department, Division of Psychiatry, University College London, London, UK.
University College London · GBMRC Clinical Trials Unit at UCL · GBUniversity of Suffolk · GBEdwards (United Kingdom) · GBNorth East London NHS Foundation Trust · GBQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with intellectual disability (ID) are more likely to experience chronic depression compared with the general population, which may be compounded by loneliness and lower levels of social support. Befriending aims to provide social support and promote engagement in community activities. No randomised controlled trials have examined whether befriending improves symptoms of depression and social outcomes in people with ID. The aim of this pilot trial was to assess the feasibility and acceptability of a future larger trial of one-to-one befriending by volunteers in people with ID and depressive symptoms.

methodsParticipants were adults with mild or moderate ID with a score of 5 or more on the Glasgow Depression Scale for People with Learning Disabilities (GDS-LD). They were randomised to the intervention arm (matched to a volunteer befriender for 6 months) or the control arm (usual care). Volunteers received training and supervision provided by two community befriending schemes. The main outcomes were feasibility of recruitment (minimum target n = 35), retention rate of participants, adherence (minimum 10 meetings), acceptability of the intervention, changes in depressive symptoms (assessed at baseline and 6 months) and feasibility of collecting data for a health economic analysis.

resultsRecruitment was challenging, and only 16 participants with ID and 10 volunteers were recruited. Six participants were matched with a volunteer and no participants dropped out (except for two volunteers). Four participants completed 10 meetings (mean 11.8). Befriending was thought to be acceptable, but modifications were suggested. An exploratory analysis suggested that GDS-LD score was lower in the intervention group compared with the control group after adjusting for baseline scores, but not significant (adjusted mean difference: -4.0; 95% confidence interval: -11.2 to 3.2).

conclusionsA large trial would not be feasible based on the recruitment strategies employed in this study. A further feasibility study addressing these challenges or the use of other study designs should be considered.

Indexed as

DepressionIntellectual DisabilityAdultFeasibility StudiesHumansLonelinessPilot ProjectsQuality of LifeVolunteersBefriendingDepressive symptomsIntellectual disabilityPilot studyRandomised controlled trialVolunteers

Identifiers

PMID34570405
PMCPMC9291894
OpenAlexW3204493189

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.