ArticleBiological trace element research2022
Association Between Iodine Nutritional Status and Adverse Pregnancy Outcomes in Beijing, China: a Single-Center Cohort Study.
Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Maternal Iodine Status and Birth Outcomes: A Systematic Literature Review and Meta-Analysis.Nutrients · 2023Pooled it
- Stage-specific variations in urinary and salt iodine among pregnant women in Beijing.Frontiers in nutrition · 2026Article
- Iodine Deficiency and Excess in Brazilian Pregnant Women: A Multicenter Cross-Sectional Study (EMDI-Brazil).Nutrients · 2025Article
- The relationship between excessive iodine during pregnancy and adverse pregnancy complications.Endocrine · 2025Article
- Association between individual urinary iodine concentrations in pregnant women and maternal/newborn outcomes.Endocrine connections · 2025Article
- Exploring the Correlation Between Varied Serum Iodine Nutritional Levels and Anti-Thyroglobulin Antibodies.Biological trace element research · 2025Article
- Impact of iodine nutritional levels in urban and rural pregnant women on neonatal growth indicators: a cohort study in Xinjiang, China.Frontiers in nutrition · 2025Article
- A "Pincer" Type of Acridine-Triazole Fluorescent Dye for Iodine Detection by Both 'Naked-Eye' Colorimetric and Fluorometric Modes.Molecules (Basel, Switzerland) · 2024Article
- Article
- Correlation between thyroid function indices and urine iodine levels in patients with nodular goiter.American journal of translational research · 2023Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Iodine is an essential trace element for humans and the main raw material for thyroid hormone synthesis. However, the association between iodine nutritional status and adverse pregnancy outcomes in different regions remains controversial. This single-center cohort study was focused on the association between iodine nutritional status and adverse pregnancy outcomes in Beijing, China. We enrolled 726 pregnant women who were registered at the Peking University International Hospital between February 2017 and December 2019. To analyze the association between iodine nutritional status variations and adverse pregnancy outcomes, this study cohort included 390 (53.72%) participants with iodine deficiency, 206 (28.37%) with an adequate iodine level, 103 (14.19%) with a more than adequate iodine level, and 27 (3.72%) with iodine excess, according to the urinary iodine (UI) status of pregnant women. After adjusting for age, body mass index, parity, and history of spontaneous abortion, we identified iodine deficiency as a risk factor for anti-thyroid peroxidase antibody (TPOAb) positivity [odds ratio (OR), 3.646; 95% confidence interval (95% CI), 1.658-8.017], anti-thyroglobulin antibody (TGAb) positivity (OR, 3.109; 95% CI, 1.465-6.599), and thyroid autoimmunity (OR, 2.885; 95% CI, 1.539-5.407). There was a non-linear relationship between UI and the concentrations of TPOAb and TGAb (P
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