SynthesisLung2021
Left Upper Lobectomy for Lung Cancer as a Risk Factor for Cerebral Infarction: A Systematic Review and Meta-Analysis.
Synthesis in Lung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Predictive value of systemic immune-inflammatory markers for lung cancer-associated cerebral infarction: a retrospective cohort study.American journal of cancer research · 2026Article
- Beyond resection: imaging findings of expected and complicated postoperative changes in lung cancer.Japanese journal of radiology · 2025Review
- A Case of Postoperative Wernicke Encephalopathy Mimicking Cerebellar Infarction Complicated by Postoperative Nausea and Vomiting: A Critical Diagnostic Pitfall for Thoracic Surgeons.Surgical case reports · 2025Article
- Pulmonary vein stump thrombosis and organ infarction after lung lobectomy.Journal of anesthesia · 2024Review
- Proximal ligation technique prevents thrombus formation in the pulmonary vein stump after lobectomy.Surgery today · 2024Article
- Postoperative cerebral infarction and arrhythmia after pulmonary lobectomy in Japan: a retrospective analysis of 77,060 cases in a national clinical database.Surgery today · 2023Article
- Lung Lobectomy Is an Embolic Risk Factor for Cerebral Infarction, Even in the Long-term Postoperative Phase.Internal medicine (Tokyo, Japan) · 2023Article
- Do blood flow patterns in the left atriums differ between left upper lobectomy and other lobectomies? A computational study.Frontiers in cardiovascular medicine · 2023Article
- A case of cerebral infarction due to aplastic or twig-like middle cerebral artery after lung cancer surgery.Journal of surgical case reports · 2022Article
- 4D Flow MR Imaging of the Left Atrium: What is Non-physiological Blood Flow in the Cardiac System?Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022Article
- LUNG Year in Review: 2021.Lung · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited evidence on the role of the type of lobectomy after primary lung cancer with postoperative cerebral infarction (CI). The purpose of this review was to evaluate the role of left upper lobectomy (LUL) in pulmonary vein thrombosis (PVT) and eventual CI.
methodsA search was performed on MEDLINE, Embase, and Web of Science from inception to January 2021. Prospective and retrospective cohort studies investigating the association between types of lobectomies for primary lung cancer with PVT and/or CI were included. Newcastle-Ottawa Scale (NOS) was used to assess the risk of bias. A random-effect model meta-analysis was utilized if significant heterogeneity was observed.
resultsTwelve studies, including 5266 patients were included. The majority of studies were having a low risk of bias. LUL was associated with higher likelihood of CI (OR
conclusionThe results of this review indicate that LUL after lung cancer is an independent risk factor for developing CI without underlying PVT. In addition, the risk of CI increases significantly when PVT develops after LUL. LUL is also a risk factor for PVT. A more frequent follow-up may be beneficial in lung cancer patients after LUL, especially in those with diabetes or undergoing adjuvant systemic therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.