Evidence map›Paper›PMID 34570107›Full record

ArticleJournal of visualized experiments : JoVE2021

Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes.

Schuyler D Vickers, Dominique C Saporito, Roberta Leonardi

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Schuyler D Vickers *Department of Biochemistry, School of Medicine, West Virginia University.
Dominique C Saporito *Department of Biochemistry, School of Medicine, West Virginia University.
Roberta LeonardiDepartment of Biochemistry, School of Medicine, West Virginia University; roleonardi@hsc.wvu.edu.
West Virginia University · US

Funding

Changes in Coenzyme A Levels are a Key Mechanism Regulating Metabolic PathwaysR35GM119528 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Roberta Leonardi · 2016 to 2026
$4.4M
NIGMS NIH HHS R35 GM119528
6 · The paper itself

Abstract

Fatty acid β-oxidation is a key metabolic pathway to meet the energy demands of the liver and provide substrates and cofactors for additional processes, such as ketogenesis and gluconeogenesis, which are essential to maintain whole-body glucose homeostasis and support extra-hepatic organ function in the fasted state. Fatty acid β-oxidation occurs within the mitochondria and peroxisomes and is regulated through multiple mechanisms, including the uptake and activation of fatty acids, enzyme expression levels, and availability of cofactors such as coenzyme A and NAD

Indexed as

Fatty AcidsGluconeogenesisAnimalsHepatocytesLiverMiceOxidation-ReductionFatty Acids

Identifiers

PMID34570107
PMCPMC9035282
OpenAlexW3201048705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.