ArticleNursing research
Exercise Training and Cognitive Function in Kidney Disease: Protocol for a Pilot Randomized Controlled Trial.
Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Effects of different exercises on renal and cardiovascular function in adult patients with chronic kidney disease not receiving dialysis: a network meta-analysis.BMC nephrology · 2026Article
- Interventions to improve cognitive performance in chronic kidney disease: A scoping review.PloS one · 2025Article
- The Relationship Between Sleep and Brain Function in Older Adults With Chronic Kidney Disease and Self-Identified Cognitive Impairment.Journal of gerontological nursing · 2023Article
- Physical function, functional capacity, cognition, and brain structure and function in older adults with chronic kidney disease (CKD).Geriatric nursing (New York, N.Y.)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundChronic kidney disease (CKD) is extremely common in older adults and is associated with cognitive impairment. It is hypothesized that accelerated cognitive decline in CKD results from a vascular dysfunction-induced reduction in the integrity of the brain white matter.
objectiveThe aim of this study was to describe the protocol for a study to evaluate whether exercise training provides a cerebroprotective effect by improving cerebrovascular health.
methodsThis is a randomized controlled trial investigating feasibility and effect size.
resultsParticipants will be randomized to either a 24-week, home-based, walking program or a usual care group. Participants will undergo evaluation of cognitive function, brain structure via magnetic reasoning imaging, physical function, physical activity, and vascular function. The primary outcome is change in cognitive function. DISCUSSION: The findings of this study will help determine whether exercise training influences cognitive function during a therapeutic window in the disease process of cognitive impairment in older adults with CKD.
conclusionThis protocol describes a study to evaluate cognition and brain structure following a home-based exercise program to an at-risk population.
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Registered trials
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