ArticleInternational journal of stroke : official journal of the International Stroke Society2022
The coronal plane maximum diameter of deep intracerebral hemorrhage predicts functional outcome more accurately than hematoma volume.
Article in International journal of stroke : official journal of the International Stroke Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Outcomes and risk factors of hemorrhage in patients with resected brain metastases.International journal of cancer · 2026Article
- Improving the Robustness of Deep Learning Models in Predicting Hematoma Expansion from Admission Head CT.AJNR. American journal of neuroradiology · 2025Article
- Article
- Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography.Applied sciences (Basel, Switzerland) · 2025Article
- A Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence.Bioengineering (Basel, Switzerland) · 2024Article
- Peri-hematomal edema shape features related to 3-month outcome in acute supratentorial intracerebral hemorrhage.European stroke journal · 2024Article
- Radiomic Features of Acute Cerebral Hemorrhage on Non-Contrast CT Associated with Patient Survival.Diagnostics (Basel, Switzerland) · 2024Article
- Time-Dependent Changes in Hematoma Expansion Rate after Supratentorial Intracerebral Hemorrhage and Its Relationship with Neurological Deterioration and Functional Outcome.Diagnostics (Basel, Switzerland) · 2024Article
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16 authors.
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Abstract
backgroundAmong prognostic imaging variables, the hematoma volume on admission computed tomography (CT) has long been considered the strongest predictor of outcome and mortality in intracerebral hemorrhage.
aimsTo examine whether different features of hematoma shape are associated with functional outcome in deep intracerebral hemorrhage.
methodsWe analyzed 790 patients from the ATACH-2 trial, and 14 shape features were quantified. We calculated Spearman's Rho to assess the correlation between shape features and three-month modified Rankin scale (mRS) score, and the area under the receiver operating characteristic curve (AUC) to quantify the association between shape features and poor outcome defined as mRS>2 as well as mRS > 3.
resultsAmong 14 shape features, the maximum intracerebral hemorrhage diameter in the coronal plane was the strongest predictor of functional outcome, with a maximum coronal diameter >∼3.5 cm indicating higher three-month mRS scores. The maximum coronal diameter versus hematoma volume yielded a Rho of 0.40 versus 0.35 (
conclusionsA coronal-plane maximum diameter measurement offers greater prognostic value in deep intracerebral hemorrhage than hematoma volume. This simple shape metric may expedite assessment of admission head CTs, offer a potential biomarker for hematoma size eligibility criteria in clinical trials, and may substitute volume in prognostic intracerebral hemorrhage scoring systems.
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