ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2022
Dementia in Africa: Current evidence, knowledge gaps, and future directions.
Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
97 citing papers in PubMed, 4 syntheses or guidelines pooled it, 154 citations in OpenAlex.
- Utilisation of brain MRI for the diagnosis of dementia in low and middle-income countries: systematic review and meta-analysis.BMJ open · 2026Pooled it
- Life-course policies to address high dementia risk in nigerian women should synergistically combat poor education and early-life nutrition disparities.BMC neurology · 2026Pooled it
- Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Cognitive Stimulation Therapy for older people with Dementia in Africa: A Scoping Review.Open research Africa · 2023Pooled it
- Neuropsychiatry genetics in Africa.Nature communications · 2026Review
- Toward culturally responsive dementia recognition and assessment in Sub-Saharan Africa: lessons from empirical research in West Africa.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Plasma proteomic profiles of Alzheimer's disease and neurodegeneration in African cohorts.Nature communications · 2026Article
- Article
- Sex differences in alcohol use and perceptions of cognitive health in rural Uganda.BMC geriatrics · 2026Article
- Epidemiologic and clinical features of Alzheimer's disease: a hospital study based on the memory clinic in Abidjan, Côte D'ivoire, Sub-Saharan Africa.BMC neurology · 2026Article
- Prevalence of dementia among older persons in Northern Uganda, a cross-sectional study.African health sciences · 2026Article
- A Global, Regional, and National Survey on Burden and Quality of Care Index of Alzheimer's Disease and Other Dementias in Adults Aged 55 and Above: The Global Burden of Disease Study 1990-2021.Neuroepidemiology · 2026Article
- Contextual variability in under-diagnosed cardiometabolic disease and cognitive vulnerability among populations at high risk for Alzheimer's disease and related dementias.Research square · 2026Article
- Community perceptions and barriers to brain health and dementia care in rural communities in Cameroon: a qualitative study.BMC neurology · 2026Article
- Cognitive aging across the life course in a low-income context: evidence from Malawi.International journal of epidemiology · 2026Article
- Contextual variability in under-diagnosed cardiometabolic disease and cognitive vulnerability among populations at high risk for Alzheimer's disease and related dementias.NPJ dementia · 2026Article
- Blood-based biomarkers of Alzheimer's disease and neurodegeneration in an indigenous African cohort using both Simoa and NULISA platforms.NPJ dementia · 2026Article
- Agreement and Comparative Performance of Cognitive Testing, Visual MRI Rating, and Automated Brain Morphometry in Older Adults with Suspected Dementia in Uganda.Degenerative neurological and neuromuscular disease · 2026Article
- Gut microbiota and brain aging: a comparative review of African and western populations.Frontiers in aging neuroscience · 2026Review
- Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 20 institutions in 16 countries.
Funding
Abstract
In tandem with the ever-increasing aging population in low and middle-income countries, the burden of dementia is rising on the African continent. Dementia prevalence varies from 2.3% to 20.0% and incidence rates are 13.3 per 1000 person-years with increasing mortality in parts of rapidly transforming Africa. Differences in nutrition, cardiovascular factors, comorbidities, infections, mortality, and detection likely contribute to lower incidence. Alzheimer's disease, vascular dementia, and human immunodeficiency virus/acquired immunodeficiency syndrome-associated neurocognitive disorders are the most common dementia subtypes. Comprehensive longitudinal studies with robust methodology and regional coverage would provide more reliable information. The apolipoprotein E (APOE) ε4 allele is most studied but has shown differential effects within African ancestry compared to Caucasian. More candidate gene and genome-wide association studies are needed to relate to dementia phenotypes. Validated culture-sensitive cognitive tools not influenced by education and language differences are critically needed for implementation across multidisciplinary groupings such as the proposed African Dementia Consortium.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.