Evidence map›Paper›PMID 34569684›Full record

ArticleInternational journal of clinical practice2021

Obesity is associated with a greater number of long-term post-COVID symptoms and poor sleep quality: A multicentre case-control study.

César Fernández-de-Las-Peñas, Juan Torres-Macho, Carlos M Elvira-Martínez, Luis J Molina-Trigueros, Tomas Sebastián-Viana, Valentín Hernández-Barrera

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 6 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 6 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  5. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
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  13. Sex Differences in Long COVID.JAMA network open · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

César Fernández-de-Las-PeñasDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos (URJC), Madrid, Spain.
Juan Torres-MachoDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Carlos M Elvira-MartínezDepartment of Clinical Documentation, Hospital Clínico San Carlos. Madrid, Spain.
Luis J Molina-TriguerosDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos (URJC), Madrid, Spain.
Tomas Sebastián-VianaDepartment of Physical Therapy, Hospital Universitario Fuenlabrada, Madrid, Spain.
Valentín Hernández-BarreraDepartment of Public Health, Universidad Rey Juan Carlos (URJC), Madrid, Spain.
Hospital Universitario de Fuenlabrada · ESUniversidad Rey Juan Carlos · ESHospital Clínico San Carlos · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a risk factor associated with higher mortality at the acute phase of COVID-19; however, its influence on post-COVID symptoms is not known.

objectiveOur aim was to investigate if obesity is a risk factor for the presence of long-term post-COVID symptoms in hospitalised COVID-19 survivors.

methodsA multicentre case-control study including patients hospitalised during the first wave of the pandemic was performed. Patients with obesity were recruited as cases. Two age- and sex-matched patients without obesity per case were considered as controls. Clinical and hospitalisation data were collected from the hospital medical records. Patients were scheduled for a telephonic interview. A list of post-COVID symptoms was systematically evaluated, but participants were free to report any symptom. Anxiety/depressive levels and sleep quality were evaluated with the hospital anxiety and depression scale (HADS) and Pittsburgh sleep quality index (PSQI), respectively.

resultsOverall, 88 patients with obesity and 176 without obesity were assessed 7.2 months after the hospital discharge. The most prevalent post-COVID symptoms were fatigue and dyspnea. No significant difference in the prevalence of fatigue, dyspnea, anxiety, depression and limitations of daily living activities was observed between people with and without obesity. Obesity was independently associated with a greater number of post-COVID symptoms (IRR 1.56, 95% CI 1.24-1.95, P < .001) and poor sleep quality (OR 2.10, 95% CI 1.13-3.83, P = .02).

conclusionsThis study found that obesity was associated with a greater number of long-term post-COVID symptoms and poor sleep quality in hospitalised COVID-19 patients.

Indexed as

COVID-19AnxietyCase-Control StudiesHumansObesitySARS-CoV-2Sleep Quality

Identifiers

PMID34569684
PMCPMC8646300
OpenAlexW3204213344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.